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Thomas Ulshofer

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Citations 194
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Recent Articles
1.
Erkoc P, Schiffmann S, Ulshofer T, Henke M, Marner M, Kramer J, et al.
iScience . 2024 Jul; 27(7):110209. PMID: 39021791
Arthropod venoms contain bioactive molecules attractive for biomedical applications. However, few of these have been isolated, and only a tiny number has been characterized. Pseudoscorpions are small arachnids whose venom...
2.
Poor S, Henke M, Ulshofer T, Kohm M, Behrens F, Burkhardt H, et al.
Rheumatology (Oxford) . 2023 Apr; 62(12):3993-3999. PMID: 37079726
Objective: We investigated the impact of concomitant MTX on ustekinumab (UST) levels and antidrug antibody (ADA) formation in PsA and evaluated consequences in pharmacodynamics and pharmacokinetics. Methods: We conducted a...
3.
Schiffmann S, Henke M, Seifert M, Ulshofer T, Roser L, Magari F, et al.
Int J Mol Sci . 2023 Mar; 24(6). PMID: 36982945
A promising new approach to broad spectrum antiviral drugs is the inhibition of the eukaryotic translation initiation factor 4A (elF4A), a DEAD-box RNA helicase that effectively reduces the replication of...
4.
Erkoc P, von Reumont B, Luddecke T, Henke M, Ulshofer T, Vilcinskas A, et al.
Toxins (Basel) . 2022 Dec; 14(12). PMID: 36548715
The venom of honeybees is composed of numerous peptides and proteins and has been used for decades as an anti-inflammatory and anti-cancer agent in traditional medicine. However, the bioactivity of...
5.
Schiffmann S, Gunne S, Ulshofer T, Henke M, Roser L, Schneider A, et al.
Pharmaceuticals (Basel) . 2022 Sep; 15(9). PMID: 36145307
We characterized the in vitro safety and bioavailability profile of silvestrol, a compound effective against various viruses, such as corona- and Ebolaviruses, with an EC value of about 5 nM....
6.
Roser L, Erkoc P, Ingelfinger R, Henke M, Ulshofer T, Schneider A, et al.
Biomed Pharmacother . 2022 Feb; 148:112734. PMID: 35190352
Lichen extracts containing, among other compounds, depsides such as evernic acid, atranorin, and lecanoric acid possess anti-proliferative effects. We aimed to identify lichen metabolites that are responsible for the observed...
7.
El-Hindi K, Brachtendorf S, Hartel J, Oertel S, Birod K, Merz N, et al.
Int J Mol Sci . 2022 Feb; 23(3). PMID: 35163788
To better understand the role of sphingolipids in the multifactorial process of inflammatory bowel disease (IBD), we elucidated the role of CerS4 in colitis and colitis-associated cancer (CAC). For this,...
8.
Crodel C, Jentsch-Ullrich K, Reiser M, Jacobasch L, Sauer A, Tesch H, et al.
J Cancer Res Clin Oncol . 2021 Nov; 148(10):2693-2705. PMID: 34807311
Purpose: Patients with polycythemia vera (PV) show an elevated incidence of thromboembolic complications and decreased survival when compared to age-matched healthy individuals. Hypercellularity as indicated by elevated hematocrit, pathophysiological changes...
9.
Reus P, Schneider A, Ulshofer T, Henke M, Bojkova D, Cinatl J, et al.
Life (Basel) . 2021 Aug; 11(8). PMID: 34440554
Methods: We have investigated the influence of the ACE inhibitors (lisinopril, captopril) and the AT antagonists (telmisartan, olmesartan) on the level of ACE2 mRNA and protein expression as well as...
10.
Schiffmann S, Gunne S, Henke M, Ulshofer T, Steinhilber D, Sethmann A, et al.
J Inflamm Res . 2021 Jun; 14:2569-2582. PMID: 34163212
Background: Sodium bituminosulfonate is derived from naturally occurring sulphur-rich oil shale and is used for the treatment of the inflammatory skin disease rosacea. Major molecular players in the development of...