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Sandra Trautmann

Explore the profile of Sandra Trautmann including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 532
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Recent Articles
1.
Hahnefeld L, Hackel J, Trautmann S, Angioni C, Schreiber Y, Gurke R, et al.
Am J Physiol Cell Physiol . 2024 Oct; 327(6):C1462-C1480. PMID: 39437447
Perceived stress is thought to contribute to the pathogenesis of metabolic, vascular, mental, and immune diseases, with different susceptibilities in women and men. The present study investigated if and how...
2.
Volk L, Bruun J, Trautmann S, Thomas D, Schwalm S, Pfeilschifter J, et al.
Pflugers Arch . 2024 Oct; 476(12):1895-1911. PMID: 39392480
Sphingosine-1-phosphate (S1P) is a ubiquitous lipid mediator, acting via specific G-protein-coupled receptors (GPCR) and intracellularly. Previous work has shown that deletion of S1P lyase caused a chronic elevation of cytosolic...
3.
Lotsch J, Gasimli K, Malkusch S, Hahnefeld L, Angioni C, Schreiber Y, et al.
Elife . 2024 Sep; 13. PMID: 39347767
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a serious therapy-limiting side effect of commonly used anticancer drugs. Previous studies suggest that lipids may play a role in CIPN. Therefore, the present...
4.
Standoli S, Rapino C, Di Meo C, Rudowski A, Kampfer-Kolb N, Volk L, et al.
Int J Mol Sci . 2023 May; 24(10). PMID: 37239854
Microglia, the resident immune cells of the central nervous system, play important roles in brain homeostasis as well as in neuroinflammation, neurodegeneration, neurovascular diseases, and traumatic brain injury. In this...
5.
Lucaciu A, Trautmann S, Thomas D, Lachner K, Brunkhorst R, Subburayalu J
J Integr Neurosci . 2022 Nov; 21(6):161. PMID: 36424740
Background: Cardiovascular diseases like stroke cause changes to sphingolipid mediators like sphingosine 1-phosphate (S1P) or its ceramide analogs, which bear the potential to either alleviate or exacerbate the neurological damage....
6.
Hafizi R, Imeri F, Stepanovska Tanturovska B, Manaila R, Schwalm S, Trautmann S, et al.
Int J Mol Sci . 2022 Jun; 23(11). PMID: 35682566
Erythropoietin (Epo) is a crucial hormone regulating red blood cell number and consequently the hematocrit. Epo is mainly produced in the kidney by interstitial fibroblast-like cells. Previously, we have shown...
7.
Nieraad H, de Bruin N, Arne O, Hofmann M, Pannwitz N, Resch E, et al.
Front Aging Neurosci . 2022 May; 14:876826. PMID: 35572151
A causal contribution of hyperhomocysteinemia to cognitive decline and Alzheimer's disease (AD), as well as potential prevention or mitigation of the pathology by dietary intervention, have frequently been subjects of...
8.
Glueck M, Koch A, Brunkhorst R, Ferreiros Bouzas N, Trautmann S, Schaefer L, et al.
FEBS J . 2022 Mar; 289(18):5670-5681. PMID: 35320610
Sphingosine 1-phosphate (S1P) is a lipid mediator with numerous biological functions. The term 'S1P' mainly refers to the sphingolipid molecule with a long-chain sphingoid base of 18 carbon atoms, d18:1...
9.
El-Hindi K, Brachtendorf S, Hartel J, Oertel S, Birod K, Merz N, et al.
Int J Mol Sci . 2022 Feb; 23(3). PMID: 35163788
To better understand the role of sphingolipids in the multifactorial process of inflammatory bowel disease (IBD), we elucidated the role of CerS4 in colitis and colitis-associated cancer (CAC). For this,...
10.
Hansen L, Lohfink N, Vutukuri R, Kestner R, Trautmann S, Hecht M, et al.
J Neurosci . 2021 Dec; 42(10):1908-1929. PMID: 34903569
The precise regulation of blood-brain barrier (BBB) permeability for immune cells and blood-borne substances is essential to maintain brain homeostasis. Sphingosine-1-phosphate (S1P), a lipid signaling molecule enriched in plasma, is...