Sabine Grosch
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Explore the profile of Sabine Grosch including associated specialties, affiliations and a list of published articles.
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76
Citations
1973
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Recent Articles
1.
Merz N, Schilling K, Thomas D, Hahnefeld L, Grosch S
Molecules
. 2025 Jan;
30(2).
PMID: 39860245
Protein S-palmitoylation is the process by which a palmitoyl fatty acid is attached to a cysteine residue of a protein via a thioester bond. A range of methodologies are available...
2.
Merz N, Hartel J, Grosch S
Pflugers Arch
. 2024 Apr;
476(12):1803-1816.
PMID: 38635059
The integrity of the colon and the development of colon cancer depend on the sphingolipid balance in colon epithelial cells. In this review, we summarize the current knowledge on how...
3.
El Hindi K, Brachtendorf S, Hartel J, Renne C, Birod K, Schilling K, et al.
Biochim Biophys Acta Mol Basis Dis
. 2023 Oct;
1870(1):166906.
PMID: 37802156
Sphingolipids are important for the physicochemical properties of cellular membranes and deregulated in tumors. In human colon cancer tissue ceramide synthase (CerS) 4 and CerS5 are reduced which correlates with...
4.
Zimmermann T, Staebler S, Taudte R, Unuvar S, Grosch S, Arndt S, et al.
Cancers (Basel)
. 2023 Feb;
15(4).
PMID: 36831408
Cold atmospheric plasma (CAP) describes a partially ionized gas carrying large amounts of reactive oxygen (ROS) and nitrogen species (RNS). Numerous studies reported strong antitumor activity of CAP, thus rendering...
5.
Hartel J, Merz N, Grosch S
Front Pharmacol
. 2022 Sep;
13:1002915.
PMID: 36176439
The concept of proper resolution of inflammation rather than counteracting it, gained a lot of attention in the past few years. Re-assembly of tissue and cell homeostasis as well as...
6.
Sekar D, Dillmann C, Sirait-Fischer E, Fink A, Zivkovic A, Baum N, et al.
Cancer Res
. 2022 Apr;
82(8):1617-1632.
PMID: 35425959
Significance: This study shows that inhibiting the production of ether-phosphatidylserine by targeting phosphatidylserine synthase PTDSS1 limits tumor-associated macrophage expansion and breast tumor growth.
7.
El-Hindi K, Brachtendorf S, Hartel J, Oertel S, Birod K, Merz N, et al.
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163788
To better understand the role of sphingolipids in the multifactorial process of inflammatory bowel disease (IBD), we elucidated the role of CerS4 in colitis and colitis-associated cancer (CAC). For this,...
8.
Kahnt A, Angioni C, Gobel T, Hofmann B, Roos J, Steinbrink S, et al.
Front Pharmacol
. 2022 Feb;
12:782584.
PMID: 35126121
5-Lipoxygenase (5-LO) is the key enzyme in the formation of pro-inflammatory leukotrienes (LT) which play an important role in a number of inflammatory diseases. Accordingly, 5-LO inhibitors are frequently used...
9.
Spohner A, Jakobi K, Trautmann S, Thomas D, Schumacher F, Kleuser B, et al.
Int J Mol Sci
. 2021 Oct;
22(19).
PMID: 34638955
Sphingosine 1 phosphate (S1P) lyase () catalyses the irreversible cleavage of S1P and thereby the last step of sphingolipid degradation. Loss of in humans and mice leads to accumulation of...
10.
Albi E, Grosch S
Int J Mol Sci
. 2021 Apr;
22(7).
PMID: 33807133
Lipids are structural components of membranes [...].