Thomas Topilko
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Explore the profile of Thomas Topilko including associated specialties, affiliations and a list of published articles.
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11
Citations
342
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Recent Articles
1.
Fayad S, Reynolds L, Torquet N, Tolu S, Mondoloni S, Nguyen C, et al.
PLoS Biol
. 2024 Oct;
22(10):e3002850.
PMID: 39446878
Individual animals differ in their traits and preferences, which shape their social interactions, survival, and susceptibility to disease, including addiction. Nicotine use is highly heterogenous and has been linked to...
2.
Reynolds L, Gulmez A, Fayad S, Campos R, Rigoni D, Nguyen C, et al.
Nat Commun
. 2024 Oct;
15(1):9017.
PMID: 39424848
How nicotine acts on developing neurocircuitry in adolescence to promote later addiction vulnerability remains largely unknown, but may hold the key for informing more effective intervention efforts. We found transient...
3.
Fadahunsi N, Petersen J, Metz S, Jakobsen A, Vad Mathiesen C, Silke Buch-Rasmussen A, et al.
Sci Adv
. 2024 Mar;
10(9):eadg2636.
PMID: 38427737
Human genome-wide association studies (GWAS) suggest a functional role for central glutamate receptor signaling and plasticity in body weight regulation. Here, we use UK Biobank GWAS summary statistics of body...
4.
Gerschenfeld G, Coulpier F, Gresset A, Pulh P, Job B, Topilko T, et al.
Elife
. 2023 Dec;
12.
PMID: 38095361
In addition to their roles in protecting nerves and increasing conduction velocity, peripheral glia plays key functions in blood vessel development by secreting molecules governing arteries alignment and maturation with...
5.
Carton-Leclercq A, Carrion-Falgarona S, Baudin P, Lemaire P, Lecas S, Topilko T, et al.
Neurobiol Dis
. 2023 Nov;
188:106345.
PMID: 37926170
The neocortex is highly susceptible to metabolic dysfunction. When exposed to global ischemia or anoxia, it suffers a slowly propagating wave of collective neuronal depolarization that ultimately impairs its structure...
6.
Schneeberger M, Brice N, Pellegrino K, Parolari L, Shaked J, Page K, et al.
Nat Metab
. 2022 Dec;
5(1):183.
PMID: 36572826
No abstract available.
7.
Schneeberger M, Brice N, Pellegrino K, Parolari L, Shaked J, Page K, et al.
Nat Metab
. 2022 Nov;
4(11):1495-1513.
PMID: 36411386
Food intake and body weight are tightly regulated by neurons within specific brain regions, including the brainstem, where acute activation of dorsal raphe nucleus (DRN) glutamatergic neurons expressing the glutamate...
8.
Topilko T, Diaz S, Pacheco C, Verny F, Rousseau C, Kirst C, et al.
Neuron
. 2022 Feb;
110(8):1385-1399.e8.
PMID: 35123655
Optimizing reproductive fitness in mammalians requires behavioral adaptations during pregnancy. Maternal preparatory nesting is an essential behavior for the survival of the upcoming litter. Brain-wide immediate early gene mapping in...
9.
Kirst C, Skriabine S, Vieites-Prado A, Topilko T, Bertin P, Gerschenfeld G, et al.
Cell
. 2020 Feb;
180(4):780-795.e25.
PMID: 32059781
The cerebral vasculature is a dense network of arteries, capillaries, and veins. Quantifying variations of the vascular organization across individuals, brain regions, or disease models is challenging. We used immunolabeling...
10.
Voigt F, Kirschenbaum D, Platonova E, Pages S, Campbell R, Kastli R, et al.
Nat Methods
. 2019 Sep;
16(11):1105-1108.
PMID: 31527839
Light-sheet microscopy is an ideal technique for imaging large cleared samples; however, the community is still lacking instruments capable of producing volumetric images of centimeter-sized cleared samples with near-isotropic resolution...