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» Authors » Thomas Thykjaer

Thomas Thykjaer

Explore the profile of Thomas Thykjaer including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 17
Citations 1218
Followers 0
Related Specialties
Oncology
Molecular Biology
Genetics
Top 10 Co-Authors
Torben F Orntoft
Lars Dyrskjot
Mogens Kruhoffer
Torben Orntoft
Niels Marcussen
Carsten Wiuf
Gangning Liang
Hans Wolf
Bernard Klein
Fabrice Moore
Published In
Cancer Res
Clin Cancer Res
Oncogene
Cancer Cell
J Mol Diagn
Affiliations
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Recent Articles
11.
Gene expression in the urinary bladder: a common carcinoma in situ gene expression signature exists disregarding histopathological classification
Dyrskjot L, Kruhoffer M, Thykjaer T, Marcussen N, Jensen J, Moller K, et al.
Cancer Res . 2004 Jun; 64(11):4040-8. PMID: 15173019
The presence of carcinoma in situ (CIS) lesions in the urinary bladder is associated with a high risk of disease progression to a muscle invasive stage. In this study, we...
12.
Identifying distinct classes of bladder carcinoma using microarrays
Dyrskjot L, Thykjaer T, Kruhoffer M, Jensen J, Marcussen N, Hamilton-Dutoit S, et al.
Nat Genet . 2002 Dec; 33(1):90-6. PMID: 12469123
Bladder cancer is a common malignant disease characterized by frequent recurrences. The stage of disease at diagnosis and the presence of surrounding carcinoma in situ are important in determining the...
13.
Expression profiling confirms the role of endocytic receptor megalin in renal vitamin D3 metabolism
Hilpert J, Wogensen L, Thykjaer T, Wellner M, Schlichting U, Orntoft T, et al.
Kidney Int . 2002 Oct; 62(5):1672-81. PMID: 12371967
Background: The endocytic receptor megalin constitutes the major pathway for clearance of low-molecular weight plasma proteins from the glomerular filtrate into the renal proximal tubules. Furthermore, the receptor has been...
14.
Comparison of gene expression profiling between malignant and normal plasma cells with oligonucleotide arrays
De Vos J, Thykjaer T, Tarte K, Ensslen M, Raynaud P, Requirand G, et al.
Oncogene . 2002 Oct; 21(44):6848-57. PMID: 12360412
The DNA microarray technology enables the identification of the large number of genes involved in the complex deregulation of cell homeostasis taking place in cancer. Using Affymetrix microarrays, we have...
15.
Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts
Tarte K, De Vos J, Thykjaer T, Zhan F, Fiol G, Costes V, et al.
Blood . 2002 Aug; 100(4):1113-22. PMID: 12149187
A new way to identify tumor-specific genes is to compare gene expression profiles between malignant cells and their autologous normal counterparts. In patients with multiple myeloma, a major plasma cell...
16.
Genome-wide study of gene copy numbers, transcripts, and protein levels in pairs of non-invasive and invasive human transitional cell carcinomas
Orntoft T, Thykjaer T, Waldman F, Wolf H, Celis J
Mol Cell Proteomics . 2002 Jul; 1(1):37-45. PMID: 12096139
Gain and loss of chromosomal material is characteristic of bladder cancer, as well as malignant transformation in general. The consequences of these changes at both the transcription and translation levels...
17.
Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine
Liang G, Gonzales F, Jones P, Orntoft T, Thykjaer T
Cancer Res . 2002 Feb; 62(4):961-6. PMID: 11861364
Hypermethylation of the promoters of cancer-related genes is often associated with their inactivation during tumorigenesis. Several preclinical and clinical trials have been developed to use DNA methylation inhibitors, such as...