Thomas Suply
Overview
Explore the profile of Thomas Suply including associated specialties, affiliations and a list of published articles.
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14
Citations
668
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Recent Articles
1.
Suply T, Hannedouche S, Carte N, Li J, Grosshans B, Schaefer M, et al.
Sci Signal
. 2017 Sep;
10(496).
PMID: 28900043
GPR15 is an orphan G protein-coupled receptor (GPCR) that is found in lymphocytes. It functions as a co-receptor of simian immunodeficiency virus and HIV-2 and plays a role in the...
2.
Egger C, Cannet C, Gerard C, Suply T, Ksiazek I, Jarman E, et al.
Eur J Pharmacol
. 2017 May;
809:64-72.
PMID: 28506908
Bleomycin (BLM) induced lung injury is detectable in C57BL/6 mice using magnetic resonance imaging (MRI). We investigated the effects of the fibroblast activation protein (FAP) inhibitor, PT100, in this model....
3.
Kumar N, Velic A, Soliz J, Shi Y, Li K, Wang S, et al.
Science
. 2015 Jun;
348(6240):1255-60.
PMID: 26068853
Blood gas and tissue pH regulation depend on the ability of the brain to sense CO2 and/or H(+) and alter breathing appropriately, a homeostatic process called central respiratory chemosensitivity. We...
4.
de Valliere C, Wang Y, Eloranta J, Vidal S, Clay I, Spalinger M, et al.
Inflamm Bowel Dis
. 2015 Apr;
21(6):1269-81.
PMID: 25856770
Background: A novel family of proton-sensing G protein-coupled receptors, including OGR1, GPR4, and TDAG8, was identified to be important for physiological pH homeostasis and inflammation. Thus, we determined the function...
5.
Giudici L, Velic A, Daryadel A, Bettoni C, Mohebbi N, Suply T, et al.
Cell Physiol Biochem
. 2013 Dec;
32(5):1403-16.
PMID: 24296356
Background: The proton-activated G protein-coupled receptor GPR4 is expressed in many tissues including white adipose tissue. GPR4 is activated by extracellular protons in the physiological pH range (i.e. pH 7.7...
6.
Hannedouche S, Beck V, Leighton-Davies J, Beibel M, Roma G, Oakeley E, et al.
J Biol Chem
. 2013 Aug;
288(38):27434-27443.
PMID: 23940034
TLQP-21, a peptide derived from VGF (non-acronymic) by proteolytic processing, has been shown to modulate energy metabolism, differentiation, and cellular response to stress. Although extensively investigated, the receptor for this...
7.
Egger C, Cannet C, Gerard C, Jarman E, Jarai G, Feige A, et al.
PLoS One
. 2013 May;
8(5):e63432.
PMID: 23667616
Pulmonary fibrosis can be experimentally induced in small rodents by bleomycin. The antibiotic is usually administered via the intratracheal or intranasal routes. In the present study, we investigated the oropharyngeal...
8.
Tchorz J, Suply T, Ksiazek I, Giachino C, Cloetta D, Danzer C, et al.
PLoS One
. 2012 Jan;
7(1):e30011.
PMID: 22253858
Generation of gain-of-function transgenic mice by targeting the Rosa26 locus has been established as an alternative to classical transgenic mice produced by pronuclear microinjection. However, targeting transgenes to the endogenous...
9.
Wyder L, Suply T, Ricoux B, Billy E, Schnell C, Baumgarten B, et al.
Angiogenesis
. 2011 Nov;
14(4):533-44.
PMID: 22045552
The G protein-coupled receptor GPR4 is activated by acidic pH and recent evidence indicates that it is expressed in endothelial cells. In agreement with these reports, we observe a high...
10.
Hannedouche S, Zhang J, Yi T, Shen W, Nguyen D, Pereira J, et al.
Nature
. 2011 Jul;
475(7357):524-7.
PMID: 21796212
Epstein-Barr virus-induced gene 2 (EBI2, also known as GPR183) is a G-protein-coupled receptor that is required for humoral immune responses; polymorphisms in the receptor have been associated with inflammatory autoimmune...