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Thomas Schroter

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Articles 33
Citations 231
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Recent Articles
11.
Chan A, Schummer A, Fischer S, Schroter T, Cruz-Zaragoza L, Bender J, et al.
Eur J Cell Biol . 2016 Nov; 95(12):585-597. PMID: 27823812
Peroxisomal matrix protein import is facilitated by cycling receptors that recognize their cargo proteins in the cytosol by peroxisomal targeting sequences (PTS). In the following, the assembled receptor-cargo complex is...
12.
Vondran M, Rastan A, Tillmann E, Seeburger J, Schroter T, Dhein S, et al.
Artif Organs . 2015 Sep; 40(4):334-40. PMID: 26366459
Visceral artery perfusion can be potentially affected by intra-aortic balloon pump (IABP) catheters. We utilized an animal model to quantify the acute impact of a low balloon position on mesenteric...
13.
Kiefer P, Seeburger J, Noack T, Schroter T, Linke A, Schuler G, et al.
Eur J Cardiothorac Surg . 2014 Oct; 47(6):1090-6. PMID: 25312527
Objectives: European guidelines recommend to perform transcatheter aortic valve implantation (TAVI) within a multidisciplinary heart team. However, there is a strong drive--despite existing guidelines--to perform TAVI outside of specialized centres....
14.
Yin Y, Cameron M, Lin L, Khan S, Schroter T, Grant W, et al.
ACS Med Chem Lett . 2014 Jun; 1(4):175-9. PMID: 24900192
A series of urea-based Rho kinase (ROCK) inhibitors were designed and evaluated. The discovered compounds had excellent enzyme and cellular potency, high kinase selectivity, high aqueous solubility, good porcine corneal...
15.
Schroter T
Rev Med Suisse . 2014 Mar; 10(415):286. PMID: 24624693
No abstract available.
16.
Kiefer P, Lehmkuhl L, Seeburger J, Vollroth M, Noack T, Schroter T, et al.
Ann Thorac Surg . 2013 Nov; 96(5):1880. PMID: 24182486
No abstract available.
17.
Yin Y, Lin L, Ruiz C, Khan S, Cameron M, Grant W, et al.
J Med Chem . 2013 Apr; 56(9):3568-81. PMID: 23570561
RhoA and its downstream effector ROCK mediate stress fiber formation and cell contraction through their effects on the phosphorylation of myosin light chain (MLC). Inhibition of the RhoA/ROCK pathway has...
18.
Chowdhury S, Chen Y, Fang X, Grant W, Pocas J, Cameron M, et al.
Bioorg Med Chem Lett . 2013 Feb; 23(6):1592-9. PMID: 23416002
SAR and lead optimization studies for Rock inhibitors based on amino acid-derived quinazolines are described. Studies demonstrated that these amino acid derived quinazolinones were mainly pan-Rock (I & II) inhibitors....
19.
Bakhtiary F, Dahnert I, Leontyev S, Schroter T, Hambsch J, Mohr F, et al.
J Card Surg . 2012 Nov; 28(1):59-63. PMID: 23189926
Objectives: Timing of primary repair of tetralogy of Fallot (TOF) remains controversial. We evaluated the long-term outcome of early primary treatment strategy in a patient cohort with TOF less than...
20.
Sessions E, Chowdhury S, Yin Y, Pocas J, Grant W, Schroter T, et al.
Bioorg Med Chem Lett . 2011 Oct; 21(23):7113-8. PMID: 22018789
Therapeutic interventions with Rho kinase (ROCK) inhibitors may effectively treat several disorders such as hypertension, stroke, cancer, and glaucoma. Herein we disclose the optimization and biological evaluation of potent novel...