Thomas S Kilduff
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Explore the profile of Thomas S Kilduff including associated specialties, affiliations and a list of published articles.
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83
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2386
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Recent Articles
1.
Park S, Heu J, Scheldrup G, Tisdale R, Sun Y, Haire M, et al.
Front Psychiatry
. 2025 Feb;
15:1467964.
PMID: 39944134
Introduction: This study aimed to investigate the role of TAAR2-9 in sleep/wake regulation, given TAAR1's known involvement in modulating neurotransmitter release and sleep patterns. Methods: Male TAAR2-9 knockout (KO) and...
2.
Park S, Heu J, Hoener M, Kilduff T
Int J Mol Sci
. 2024 Nov;
25(21).
PMID: 39518904
Trace amine-associated receptor 1 (TAAR1) is a negative regulator of dopamine (DA) release. The partial TAAR1 agonist RO5263397 promotes wakefulness and suppresses NREM and REM sleep in rodents and non-human...
3.
Park S, Heu J, Hoener M, Kilduff T
bioRxiv
. 2024 Sep;
PMID: 39314371
Trace amine-associated receptor 1 (TAAR1) is known to negatively regulate dopamine (DA) release. The partial TAAR1 agonist RO5263397 promotes wakefulness and suppresses NREM and REM sleep in mice, rats, and...
4.
Ratliff J, Terral G, Lutzu S, Heiss J, Mota J, Stith B, et al.
bioRxiv
. 2024 Jul;
PMID: 38948753
Behavioral states such as sleep and wake are highly correlated with specific patterns of rhythmic activity in the cortex. During low arousal states such as slow wave sleep, the cortex...
5.
Heiss J, Zhong P, Lee S, Yamanaka A, Kilduff T
Proc Natl Acad Sci U S A
. 2024 Apr;
121(16):e2316150121.
PMID: 38593074
For nearly a century, evidence has accumulated indicating that the lateral hypothalamus (LH) contains neurons essential to sustain wakefulness. While lesion or inactivation of LH neurons produces a profound increase...
6.
Ito H, Fukatsu N, Rahaman S, Mukai Y, Izawa S, Ono D, et al.
Proc Natl Acad Sci U S A
. 2023 Oct;
120(41):e2301951120.
PMID: 37796986
Narcolepsy is a sleep disorder caused by deficiency of orexin signaling. However, the neural mechanisms by which deficient orexin signaling causes the abnormal rapid eye movement (REM) sleep characteristics of...
7.
Tisdale R, Sun Y, Park S, Ma S, Haire M, Allocca G, et al.
J Sleep Res
. 2023 Sep;
33(3):e14037.
PMID: 37731248
Aversive symptoms, including insomnia experienced during opioid withdrawal, are a major drive to relapse; however, withdrawal-associated sleep symptomatology has been little explored in preclinical models. We describe here a model...
8.
Goonawardena A, Morairty S, Dell R, Orellana G, Hoener M, Wallace T, et al.
Neuropsychopharmacology
. 2023 Jun;
48(9):1418.
PMID: 37286766
No abstract available.
9.
10.
Sun Y, Tisdale R, Yamashita A, Kilduff T
Peptides
. 2023 Mar;
164:171002.
PMID: 36963505
Hypocretins/Orexins (Hcrt/Ox) are hypothalamic neuropeptides implicated in diverse functions, including body temperature regulation through modulation of sympathetic vasoconstrictor tone. In the current study, we measured subcutaneous (T) and core (T)...