Thomas P Hofer
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Explore the profile of Thomas P Hofer including associated specialties, affiliations and a list of published articles.
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15
Citations
319
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Recent Articles
1.
Wang Y, Rambold U, Fiedler P, Babushku T, Tapken C, Hoefig K, et al.
Cell Mol Immunol
. 2024 Oct;
21(12):1410-1425.
PMID: 39420111
Initially, identified as a Hodgkin lymphoma marker, CD30 was subsequently detected on a subset of human B cells within and around germinal centers (GCs). While CD30 expression is typically restricted...
2.
Chen J, Wang X, Schmalen A, Haines S, Wolff M, Ma H, et al.
Eur Respir J
. 2023 Jun;
62(2).
PMID: 37385655
Background: Virus infections drive COPD exacerbations and progression. Antiviral immunity centres on the activation of virus-specific CD8 T-cells by viral epitopes presented on major histocompatibility complex (MHC) class I molecules...
3.
Kasmann L, Taugner J, Eze C, Nieto A, Pelikan C, Florsch B, et al.
Transl Lung Cancer Res
. 2022 Aug;
11(7):1503-1509.
PMID: 35958344
Background: Concurrent platinum-based chemoradiotherapy (CRT) followed by durvalumab maintenance treatment represents the new standard of care in unresectable stage III non-small cell lung cancer (NSCLC). In this prospective hypothesis-generating single-center...
4.
Essien E, Hofer T, Atkinson M, Anastasov N
Cells
. 2022 Mar;
11(5).
PMID: 35269397
Glioblastoma stem-like cells (GSLCs) in glioblastoma limit effective treatment and promote therapeutic resistance and tumor recurrence. Using a combined radiation and drug-screening platform, we tested the combination of a histone...
5.
Esteve-Codina A, Hofer T, Burggraf D, Heiss-Neumann M, Gesierich W, Boland A, et al.
Sci Rep
. 2021 Jun;
11(1):12848.
PMID: 34145303
Chronic obstructive pulmonary disease (COPD) is a destructive inflammatory disease and the genes expressed within the lung are crucial to its pathophysiology. We have determined the RNAseq transcriptome of bronchial...
6.
Ma Y, Bauer V, Riedel T, Ahmetlic F, Homberg N, Hofer T, et al.
Cancer Lett
. 2021 Feb;
503:110-116.
PMID: 33524501
To establish strategies for immunotherapy of B-cell lymphoma, it is mandatory to gain deeper insights into the mechanisms of tumor immune escape. In a mouse model of endogenously arising lymphoma,...
7.
Heger L, Hofer T, Bigley V, de Vries I, Dalod M, Dudziak D, et al.
Front Immunol
. 2020 Oct;
11:559166.
PMID: 33101275
Currently three bona fide dendritic cell (DC) types are distinguished in human blood. Herein we focus on type 2 DCs (DC2s) and compare the three defining markers CD1c, CD172, and...
8.
Zhang L, Hofer T, Zawada A, Rotter B, Krezdorn N, Noessner E, et al.
Immunobiology
. 2020 Jun;
225(3):151958.
PMID: 32517883
Non-classical human monocytes are characterized by high-level expression of cytokines like TNF, but the mechanisms involved are elusive. We have identified miRNAs and CpG-methylation sites that are unique to non-classical...
9.
Hofer T, van de Loosdrecht A, Stahl-Hennig C, Cassatella M, Ziegler-Heitbrock L
Front Immunol
. 2019 Oct;
10:2052.
PMID: 31572354
Monocytes are subdivided into three subsets, which have different phenotypic and functional characteristics and different roles in inflammation and malignancy. When in man CD14 and CD16 monoclonal antibodies are used...
10.
Martin-Medina A, Lehmann M, Burgy O, Hermann S, Baarsma H, Wagner D, et al.
Am J Respir Crit Care Med
. 2018 Jul;
198(12):1527-1538.
PMID: 30044642
Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease characterized by lung epithelial cell injury, increased (myo)fibroblast activation, and extracellular matrix deposition. Extracellular vesicles (EVs) regulate intercellular communication by carrying...