Dorothe Burggraf
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Explore the profile of Dorothe Burggraf including associated specialties, affiliations and a list of published articles.
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27
Citations
304
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Recent Articles
1.
Esteve-Codina A, Hofer T, Burggraf D, Heiss-Neumann M, Gesierich W, Boland A, et al.
Sci Rep
. 2021 Jun;
11(1):12848.
PMID: 34145303
Chronic obstructive pulmonary disease (COPD) is a destructive inflammatory disease and the genes expressed within the lung are crucial to its pathophysiology. We have determined the RNAseq transcriptome of bronchial...
2.
Engel M, Endesfelder D, Schloter-Hai B, Kublik S, Granitsiotis M, Boschetto P, et al.
PLoS One
. 2017 Jul;
12(7):e0180859.
PMID: 28704452
Background: Changes in microbial community composition in the lung of patients suffering from moderate to severe COPD have been well documented. However, knowledge about specific microbiome structures in the human...
3.
Subramanian D, Gupta S, Burggraf D, Vom Silberberg S, Heimbeck I, Heiss-Neumann M, et al.
Eur Respir J
. 2016 May;
48(1):92-103.
PMID: 27230444
EvA (Emphysema versus Airway disease) is a multicentre project to study mechanisms and identify biomarkers of emphysema and airway disease in chronic obstructive pulmonary disease (COPD). The objective of this...
4.
Hofer T, Frankenberger M, Heimbeck I, Burggraf D, Wjst M, Wright A, et al.
J Mol Med (Berl)
. 2014 Aug;
92(12):1293-304.
PMID: 25146850
Unlabelled: We studied HLA class II molecules on blood monocyte subsets, blood dendritic cells, sputum macrophages, and monocyte-derived macrophages at the protein (flow cytometry) and mRNA level (RT-PCR) in adult...
5.
Ziegler-Heitbrock L, Frankenberger M, Heimbeck I, Burggraf D, Wjst M, Haussinger K, et al.
Eur Respir J
. 2012 Mar;
40(4):823-9.
PMID: 22441733
The EvA study is a European Union-funded project under the Seventh Framework Programme (FP7), which aims at defining new markers for chronic obstructive pulmonary disease (COPD) and its subtypes. The...
6.
Burggraf D, Vosko M, Schubert M, Stassen J, Hamann G
Thromb Haemost
. 2010 Mar;
103(5):891-900.
PMID: 20216985
Recombinant tissue plasminogen activator (rt-PA) is successfully used in human stroke, but often shows serious drawbacks. To find an alternative, we hypothesised that the novel thrombolytic microplasmin would have fewer...
7.
Burk J, Burggraf D, Vosko M, Dichgans M, Hamann G
Brain Res
. 2008 Jul;
1226:248-55.
PMID: 18586014
Clinical studies have shown that the treatment of ischemic stroke with hypothermia is promising. In this animal study, we investigated the fate of the microvasculature following focal cerebral ischemia in...
8.
Burggraf D, Trinkl A, Burk J, Martens H, Dichgans M, Hamann G
Brain Res
. 2007 Nov;
1189:189-97.
PMID: 18045575
The alpha1-integrin cell adhesion molecules, the principal endothelial receptors for basal lamina (BL) components disappear during transient ischemia. The current study investigated the localization of integrins, the time dependency and...
9.
Burggraf D, Martens H, Dichgans M, Hamann G
Thromb Haemost
. 2007 Nov;
98(5):963-9.
PMID: 18000599
Although recombinant tissue plasminogen activator (rt-PA) is successfully used for thrombolysis in human stroke, it may increase the risk of haemorrhagic complications. It was shown that the matrix metalloproteinase (MMP)...
10.
Burggraf D, Martens H, Dichgans M, Hamann G
Brain Res
. 2007 Jul;
1164:55-62.
PMID: 17644075
While recombinant tissue plasminogen activator (rt-PA) is successfully used for thrombolysis in human stroke, it may increase the risk of hemorrhagic complications. We describe the effects of different doses of...