Thomas N Sato
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Explore the profile of Thomas N Sato including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Oka Y, Sato T
Sci Rep
. 2015 Feb;
5:8571.
PMID: 25711926
Noise in gene expression renders cells more adaptable to changing environment by imposing phenotypic and functional heterogeneity on genetically identical individual cells. Hence, quantitative measurement of noise in gene expression...
12.
Okabe K, Kobayashi S, Yamada T, Kurihara T, Tai-Nagara I, Miyamoto T, et al.
Cell
. 2014 Nov;
159(3):584-96.
PMID: 25417109
Vascular and nervous systems, two major networks in mammalian bodies, show a high degree of anatomical parallelism and functional crosstalk. During development, neurons guide and attract blood vessels, and consequently...
13.
Sato Y, Yasuhara K, Kikuchi J, Sato T
Sci Rep
. 2013 Dec;
3:3475.
PMID: 24327069
Cell division is one of the most fundamental and evolutionarily conserved biological processes. Here, we report a synthetic system where we can control by design equal vs. unequal divisions. We...
14.
Murakoshi M, Saiki K, Urayama K, Sato T
PLoS One
. 2013 Nov;
8(11):e79374.
PMID: 24223934
Metabolic adaptation to limited supplies of oxygen and nutrients plays a pivotal role in health and disease. Heart attack results from insufficient delivery of oxygen and nutrients to the heart,...
15.
Omae M, Takada N, Yamamoto S, Nakajima H, Sato T
PLoS One
. 2013 Jun;
8(6):e65720.
PMID: 23799039
Development and homeostasis of organs and whole body is critically dependent on the circulatory system. In particular, the circulatory system, the railways shuttling oxygen and nutrients among various organs, is...
16.
Ding B, Nolan D, Guo P, Babazadeh A, Cao Z, Rosenwaks Z, et al.
Cell
. 2011 Nov;
147(3):539-53.
PMID: 22036563
To identify pathways involved in adult lung regeneration, we employ a unilateral pneumonectomy (PNX) model that promotes regenerative alveolarization in the remaining intact lung. We show that PNX stimulates pulmonary...
17.
Ding B, Nolan D, Butler J, James D, Babazadeh A, Rosenwaks Z, et al.
Nature
. 2010 Nov;
468(7321):310-5.
PMID: 21068842
During embryogenesis, endothelial cells induce organogenesis before the development of circulation. These findings suggest that endothelial cells not only form passive conduits to deliver nutrients and oxygen, but also establish...
18.
Hooper A, Butler J, Nolan D, Kranz A, Iida K, Kobayashi M, et al.
Cell Stem Cell
. 2009 Mar;
4(3):263-74.
PMID: 19265665
Myelosuppression damages the bone marrow (BM) vascular niche, but it is unclear how regeneration of bone marrow vessels contributes to engraftment of transplanted hematopoietic stem and progenitor cells (HSPCs) and...
19.
Wu M, Sato T
PLoS One
. 2008 Dec;
3(12):e4045.
PMID: 19107195
The heart is a vital organ that provides essential circulation throughout the body. Malfunction of cardiac pumping, thus, leads to serious and most of the times, to fatal diseases. Mechanics...
20.
Kobayashi K, Luo M, Zhang Y, Wilkes D, Ge G, Grieskamp T, et al.
Nat Cell Biol
. 2008 Dec;
11(1):46-55.
PMID: 19079247
Secreted Frizzled-related proteins (sFRPs) have emerged as key regulators of a wide range of developmental and disease processes. Most of the known functions of mammalian sFRPs have been attributed to...