Thomas H Teal
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Explore the profile of Thomas H Teal including associated specialties, affiliations and a list of published articles.
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11
Citations
516
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Recent Articles
1.
An J, Durcan L, Karr R, Briggs T, Rice G, Teal T, et al.
Arthritis Rheumatol
. 2016 Nov;
69(4):800-807.
PMID: 27863149
Objective: Type I interferon (IFN) is implicated in the pathogenesis of systemic lupus erythematosus (SLE) and interferonopathies such as Aicardi-Goutières syndrome. A recently discovered DNA-activated type I IFN pathway, cyclic...
2.
Giltiay N, Chappell C, Sun X, Kolhatkar N, Teal T, Wiedeman A, et al.
J Exp Med
. 2013 Oct;
210(12):2773-89.
PMID: 24145511
Toll-like receptor (TLR), a ligand for single-stranded RNA, has been implicated in the development of pathogenic anti-RNA autoantibodies both in systemic lupus erythematous (SLE) patients and in murine models of...
3.
Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice
Sun X, Wiedeman A, Agrawal N, Teal T, Tanaka L, Hudkins K, et al.
J Immunol
. 2013 Feb;
190(6):2536-43.
PMID: 23382559
TLR7 activation is implicated in the pathogenesis of systemic lupus erythematosus. Mice that overexpress TLR7 develop a lupus-like disease with autoantibodies and glomerulonephritis and early death. To determine whether degradation...
4.
Buechler M, Teal T, Elkon K, Hamerman J
J Immunol
. 2013 Jan;
190(3):886-91.
PMID: 23303674
Mice overexpressing TLR7 (TLR7.1 mice) are a model of systemic lupus erythematosus pathogenesis and exhibit peripheral myeloid expansion. We show that TLR7.1 mice have a dramatic expansion of splenic cells...
5.
Santer D, Wiedeman A, Teal T, Ghosh P, Elkon K
J Immunol
. 2011 Dec;
188(2):902-15.
PMID: 22147767
Immune complexes (ICs) play a pivotal role in causing inflammation in systemic lupus erythematosus (SLE). Yet, it remains unclear what the dominant blood cell type(s) and inflammation-related gene programs stimulated...
6.
Rockx B, Baas T, Zornetzer G, Haagmans B, Sheahan T, Frieman M, et al.
J Virol
. 2009 May;
83(14):7062-74.
PMID: 19420084
Several respiratory viruses, including influenza virus and severe acute respiratory syndrome coronavirus (SARS-CoV), produce more severe disease in the elderly, yet the molecular mechanisms governing age-related susceptibility remain poorly studied....
7.
Robinzon S, Dafa-Berger A, Dyer M, Paeper B, Proll S, Teal T, et al.
J Virol
. 2009 Mar;
83(11):5495-504.
PMID: 19297498
Measles virus remains a substantial cause of morbidity and mortality, producing acute infection with a potential for development of viral persistence. To study the events underlying acute and persistent measles...
8.
Pasieka T, Cilloniz C, Lu B, Teal T, Proll S, Katze M, et al.
J Virol
. 2008 Dec;
83(5):2075-87.
PMID: 19109391
Humans and mice lacking the interferon signaling molecule Stat1 are sensitive to a variety of pathogens due to their presumed inability to mount a strong innate immune response. The herpes...
9.
Baas T, Roberts A, Teal T, Vogel L, Chen J, Tumpey T, et al.
J Virol
. 2008 Jul;
82(19):9465-76.
PMID: 18632870
The relationship between immunosenescence and the host response to virus infection is poorly understood at the molecular level. Two different patterns of pulmonary host responses to virus were observed when...
10.
Wessells H, Teal T, Engel K, Sullivan C, Gallis B, Tran K, et al.
BJU Int
. 2006 Apr;
97(5):1047-52.
PMID: 16643490
Objective: To investigate whether fluid shear stress (FSS) induces endothelial nitric oxide synthase (eNOS) activity and NO production in isolated human corpus cavernosal endothelial cells (HCCECs), and whether this response...