Thomas H Pringle
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Explore the profile of Thomas H Pringle including associated specialties, affiliations and a list of published articles.
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10
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1025
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Recent Articles
1.
Wiegmann E, Westendorf E, Kalus I, Pringle T, Lubke T, Dierks T
J Biol Chem
. 2013 Aug;
288(42):30019-30028.
PMID: 23986440
The human sulfatase family has 17 members, 13 of which have been characterized biochemically. These enzymes specifically hydrolyze sulfate esters in glycosaminoglycans, sulfolipids, or steroid sulfates, thereby playing key roles...
2.
Liu C, Hanoian P, French J, Pringle T, Hammes-Schiffer S, Benkovic S
Proc Natl Acad Sci U S A
. 2013 Jun;
110(25):10159-64.
PMID: 23733948
With the rapidly growing wealth of genomic data, experimental inquiries on the functional significance of important divergence sites in protein evolution are becoming more accessible. Here we trace the evolution...
3.
Ennemann E, Radhakrishnan K, Mariappan M, Wachs M, Pringle T, Schmidt B, et al.
J Biol Chem
. 2013 Jan;
288(8):5828-39.
PMID: 23288839
Formylglycine-generating enzyme (FGE) post-translationally converts a specific cysteine in newly synthesized sulfatases to formylglycine (FGly). FGly is the key catalytic residue of the sulfatase family, comprising 17 nonredundant enzymes in...
4.
Mariotti M, Ridge P, Zhang Y, Lobanov A, Pringle T, Guigo R, et al.
PLoS One
. 2012 Apr;
7(3):e33066.
PMID: 22479358
Background: Selenium is an essential trace element in mammals due to its presence in proteins in the form of selenocysteine (Sec). Human genome codes for 25 Sec-containing protein genes, and...
5.
Miller W, Hayes V, Ratan A, Petersen D, Wittekindt N, Miller J, et al.
Proc Natl Acad Sci U S A
. 2011 Jun;
108(30):12348-53.
PMID: 21709235
The Tasmanian devil (Sarcophilus harrisii) is threatened with extinction because of a contagious cancer known as Devil Facial Tumor Disease. The inability to mount an immune response and to reject...
6.
Warren W, Hillier L, Marshall Graves J, Birney E, Ponting C, Grutzner F, et al.
Nature
. 2008 May;
453(7192):175-83.
PMID: 18464734
We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters. For example, platypuses have a coat of fur...
7.
Gande S, Mariappan M, Schmidt B, Pringle T, von Figura K, Dierks T
FEBS J
. 2008 Feb;
275(6):1118-30.
PMID: 18266766
Formylglycine-generating enzyme (FGE) catalyzes in newly synthesized sulfatases the oxidation of a specific cysteine residue to formylglycine, which is the catalytic residue required for sulfate ester hydrolysis. This post-translational modification...
8.
Miller W, Rosenbloom K, Hardison R, Hou M, Taylor J, Raney B, et al.
Genome Res
. 2007 Nov;
17(12):1797-808.
PMID: 17984227
This article describes a set of alignments of 28 vertebrate genome sequences that is provided by the UCSC Genome Browser. The alignments can be viewed on the Human Genome Browser...
9.
Janecka J, Miller W, Pringle T, Wiens F, Zitzmann A, Helgen K, et al.
Science
. 2007 Nov;
318(5851):792-4.
PMID: 17975064
A full understanding of primate morphological and genomic evolution requires the identification of their closest living relative. In order to resolve the ancestral relationships among primates and their closest relatives,...
10.
Murphy W, Pringle T, Crider T, Springer M, Miller W
Genome Res
. 2007 Feb;
17(4):413-21.
PMID: 17322288
The phylogeny of placental mammals is a critical framework for choosing future genome sequencing targets and for resolving the ancestral mammalian genome at the nucleotide level. Despite considerable recent progress...