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Thomas Gridley

Explore the profile of Thomas Gridley including associated specialties, affiliations and a list of published articles. Areas
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Articles 93
Citations 5070
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Recent Articles
1.
Martinez M, Pinz I, Preda M, Norton C, Gridley T, Hernandez A
JCI Insight . 2022 Sep; 7(21). PMID: 36166296
Maternal hyperthyroidism is associated with an increased incidence of congenital abnormalities at birth, but it is not clear which of these defects arise from a transient developmental excess of thyroid...
2.
Gridley T, Oxburgh L
Curr Top Dev Biol . 2022 Apr; 148:xi-xvii. PMID: 35461570
No abstract available.
3.
Gridley T, Murray S
Curr Top Dev Biol . 2022 Apr; 148:1-12. PMID: 35461561
For many years, the laboratory mouse has been the favored model organism to study mammalian development, biology and disease. Among its advantages for these studies are its close concordance with...
4.
Mase S, Shitamukai A, Wu Q, Morimoto M, Gridley T, Matsuzaki F
Neurosci Res . 2020 Dec; 170:122-132. PMID: 33309869
During mammalian corticogenesis, Notch signaling is essential to maintain neural stem cells called radial glial cells (RGCs) and the cortical architecture. Because the conventional knockout of either Notch1 or Notch2...
5.
Blanco-Gomez A, Hontecillas-Prieto L, Corchado-Cobos R, Garcia-Sancha N, Salvador N, Castellanos-Martin A, et al.
Cancer Res . 2020 Oct; 80(23):5216-5230. PMID: 33023950
SNAI2 overexpression appears to be associated with poor prognosis in breast cancer, yet it remains unclear in which breast cancer subtypes this occurs. Here we show that excess SNAI2 is...
6.
Blackwood C, Bailetti A, Nandi S, Gridley T, Hebert J
Front Cell Dev Biol . 2020 Mar; 8:113. PMID: 32161758
Neural stem cells in the lateral ganglionic eminence (LGE) generate progenitors that migrate through the rostral migratory stream (RMS) to repopulate olfactory bulb (OB) interneurons, but the regulation of this...
7.
Peterson S, Turner J, Harrington A, Davis-Knowlton J, Lindner V, Gridley T, et al.
Arterioscler Thromb Vasc Biol . 2018 Jun; 38(7):1576-1593. PMID: 29853569
Objective: Vascular remodeling is associated with complex molecular changes, including increased Notch2, which promotes quiescence in human smooth muscle cells. We used unbiased protein profiling to understand molecular signatures related...
8.
Basch M, Brown 2nd R, Jen H, Semerci F, Depreux F, Edlund R, et al.
Elife . 2016 Dec; 5. PMID: 27966429
The signals that induce the organ of Corti and define its boundaries in the cochlea are poorly understood. We show that two Notch modifiers, and are transiently expressed precisely at...
9.
Gridley T
Curr Top Dev Biol . 2016 Mar; 116:435-43. PMID: 26970632
In this chapter, I give my personal reflections on more than 30 years of studying developmental biology in the mouse model, spending 20 of those years doing research in Maine,...
10.
Krebs L, Norton C, Gridley T
Genesis . 2016 Jan; 54(2):86-90. PMID: 26742650
The ductus arteriosus is an arterial vessel that shunts blood flow away from the lungs during fetal life, but normally occludes after birth to establish the adult circulation pattern. Failure...