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Thomas Forest

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Citations 172
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Recent Articles
1.
Chen B, LaFranco-Scheuch L, Dong S, Hernandez L, Mei H, Zhong W, et al.
Toxicol Pathol . 2025 Feb; 53(1):45-54. PMID: 40013516
Drug-induced nephrotoxicity is a major challenge in drug discovery and development, accounting for nearly a quarter of severe adverse effects in current pharmacotherapy. Antimicrobial use may be associated with this...
2.
Abdurrachim D, Lek S, Ong C, Wong C, Zhou Y, Wee A, et al.
J Hepatol . 2024 Nov; PMID: 39612947
Background & Aims: Intra and inter-pathologist variability poses a significant challenge in metabolic dysfunction-associated steatohepatitis (MASH) biopsy evaluation, leading to suboptimal selection of patients and confounded assessment of histological response...
3.
Forest T, Achaz G, Marbouty M, Bignaud A, Thierry A, Koszul R, et al.
G3 (Bethesda) . 2024 Mar; 14(5). PMID: 38537260
The European green woodpecker, Picus viridis, is a widely distributed species found in the Western Palearctic region. Here, we assembled a highly contiguous genome assembly for this species using a...
4.
Gomes-Dos-Santos A, Lopes-Lima M, Machado A, Forest T, Achaz G, Teixeira A, et al.
GigaByte . 2023 May; 2023:gigabyte81. PMID: 37207176
Contiguous assemblies are fundamental to deciphering the composition of extant genomes. In molluscs, this is considerably challenging owing to the large size of their genomes, heterozygosity, and widespread repetitive content....
5.
Boisclair J, Bawa B, Barale-Thomas E, Bertrand L, Carter J, Crossland R, et al.
Toxicol Pathol . 2022 Aug; 50(6):793-807. PMID: 35950710
Digital toxicologic histopathology has been broadly adopted in preclinical compound development for informal consultation and peer review. There is now increased interest in implementing the technology for good laboratory practice-regulated...
6.
Forest T, Aeffner F, Bangari D, Bawa B, Carter J, Fikes J, et al.
Toxicol Pathol . 2022 Jun; 50(4):531-543. PMID: 35657014
The Society of Toxicologic Pathology's Scientific and Regulatory Policy Committee formed a working group to consider the present and future use of digital pathology in toxicologic pathology in general and...
7.
Forest T, Aeffner F, Bangari D, Bawa B, Carter J, Fikes J, et al.
Toxicol Pathol . 2022 Mar; 50(3):397-401. PMID: 35321602
Histopathologic evaluation and peer review using digital whole-slide images (WSIs) is a relatively new medium for assessing nonclinical toxicology studies in Good Laboratory Practice (GLP) environments. To better understand the...
8.
Schumacher V, Aeffner F, Barale-Thomas E, Botteron C, Carter J, Elies L, et al.
Toxicol Pathol . 2020 Dec; 49(4):720-737. PMID: 33297858
With advancements in whole slide imaging technology and improved understanding of the features of pathologist workstations required for digital slide evaluation, many institutions are investigating broad digital pathology adoption. The...
9.
Sandhu D, Kaundal A, Acharya B, Forest T, Pudussery M, Liu X, et al.
Sci Rep . 2020 Dec; 10(1):21087. PMID: 33273661
Fourteen commercial almond rootstocks were tested under five types of irrigation waters to understand the genetic, physiological, and biochemical bases of salt-tolerance mechanisms. Treatments included control (T1) and four saline...
10.
Fernandez G, Kuruvilla S, Hines C, Poignant F, Marr J, Forest T, et al.
J Toxicol Pathol . 2019 Nov; 32(4):233-243. PMID: 31719750
Brain changes associated with risperidone, a dopamine-2/serotonin-2 receptor antagonist, have been documented in rats and humans, but not in nonhuman primates. This study characterized brain changes associated with risperidone in...