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LuAnn McKinney

Explore the profile of LuAnn McKinney including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 327
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Recent Articles
1.
Keenan C, Al-Haddawi M, Bienvenu J, Bradley A, Brown P, Chen H, et al.
Toxicol Pathol . 2024 Mar; 52(1):13-20. PMID: 38445634
The Tumor Combination Guide was created at the request of the U. S. Food and Drug Administration (FDA) by a Working Group of biopharmaceutical experts from international societies of toxicologic...
2.
Forest T, Aeffner F, Bangari D, Bawa B, Carter J, Fikes J, et al.
Toxicol Pathol . 2022 Jun; 50(4):531-543. PMID: 35657014
The Society of Toxicologic Pathology's Scientific and Regulatory Policy Committee formed a working group to consider the present and future use of digital pathology in toxicologic pathology in general and...
3.
Forest T, Aeffner F, Bangari D, Bawa B, Carter J, Fikes J, et al.
Toxicol Pathol . 2022 Mar; 50(3):397-401. PMID: 35321602
Histopathologic evaluation and peer review using digital whole-slide images (WSIs) is a relatively new medium for assessing nonclinical toxicology studies in Good Laboratory Practice (GLP) environments. To better understand the...
4.
Schumacher V, Aeffner F, Barale-Thomas E, Botteron C, Carter J, Elies L, et al.
Toxicol Pathol . 2020 Dec; 49(4):720-737. PMID: 33297858
With advancements in whole slide imaging technology and improved understanding of the features of pathologist workstations required for digital slide evaluation, many institutions are investigating broad digital pathology adoption. The...
5.
Schultze A, Bennet B, Rae J, Chiang A, Frazier K, Katavolos P, et al.
Toxicol Pathol . 2020 Mar; 48(4):537-548. PMID: 32122253
Detection of test article-related effects and the determination of the adversity of those changes are the primary goals of nonclinical safety assessment studies for drugs and chemicals in development. During...
6.
Moschos S, Sander C, Wang W, Reppert S, Drogowski L, Jukic D, et al.
J Immunother . 2010 May; 33(3):316-25. PMID: 20445352
AlphaVbeta3 (alphavbeta3) is an important molecule for tumor-induced angiogenesis and is upregulated in metastatic melanoma (MM). We proposed to study the mechanism of action of etaracizumab, a monoclonal antibody targeting...
7.
Reed J, Welliver T, Sims G, McKinney L, Velozo L, Avendano L, et al.
J Infect Dis . 2009 Mar; 199(8):1128-38. PMID: 19278337
Antiviral antibody production during respiratory syncytial virus (RSV) infection in infants is poorly understood. To characterize local B lymphocyte responses, lung tissue and secretions from infants with RSV bronchiolitis were...
8.
Reed J, Brewah Y, Delaney T, Welliver T, Burwell T, Benjamin E, et al.
J Infect Dis . 2008 Nov; 198(12):1783-93. PMID: 18980502
Although respiratory syncytial virus (RSV) infection is the most important cause of bronchiolitis in infants, the pathogenesis of RSV disease is poorly described. We studied histopathologic changes in a panel...
9.
Welliver T, Garofalo R, Hosakote Y, Hintz K, Avendano L, Sanchez K, et al.
J Infect Dis . 2007 Mar; 195(8):1126-36. PMID: 17357048
Background: Respiratory syncytial virus (RSV) and influenza virus are common causes of infantile lower respiratory tract infection (LRTI). It is widely believed that both viral replication and inappropriately enhanced immune...
10.
Whitnall M, Wilhelmsen C, McKinney L, Miner V, Seed T, Jackson 3rd W
Immunopharmacol Immunotoxicol . 2003 Jan; 24(4):595-626. PMID: 12510793
We previously showed that one subcutaneous (sc) injection of 5-androstene-3beta,17beta-diol (AED) stimulated the innate immune system in mice and prevented mortality due to hemopoietic suppression after whole-body ionizing irradiation with...