Thomas Eichberger
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Explore the profile of Thomas Eichberger including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
534
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Recent Articles
1.
Laner-Plamberger S, Wolff F, Kaser-Eichberger A, Swierczynski S, Hauser-Kronberger C, Frischauf A, et al.
PLoS One
. 2013 Sep;
8(9):e75317.
PMID: 24058673
Sustained hedgehog (Hh) signaling mediated by the GLI transcription factors is implicated in many types of cancer. Identification of Hh/GLI target genes modulating the activity of other pathways involved in...
2.
Winklmayr M, Schmid C, Laner-Plamberger S, Kaser A, Aberger F, Eichberger T, et al.
BMC Mol Biol
. 2010 Jan;
11:2.
PMID: 20070907
Background: The GLI transcription factors, mediators of the hedgehog signal bind with high affinity to the consensus sequence GACCACCCA. The affinity of variant single substitutions in GLI binding sites has...
3.
Eichberger T, Kaser A, Pixner C, Schmid C, Klingler S, Winklmayr M, et al.
J Biol Chem
. 2008 Mar;
283(18):12426-37.
PMID: 18319260
Hedgehog (HH) signaling in the epidermis is primarily mediated by the zinc finger transcription factors GLI1 and GLI2. Exquisite regulation of HH/GLI signaling is crucial for proper specification of the...
4.
Kasper M, Regl G, Eichberger T, Frischauf A, Aberger F
Methods Mol Biol
. 2007 Nov;
397:67-78.
PMID: 18025714
Efficient manipulation of Hedgehog (HH)/GLI signaling activity is crucial to the analysis of molecular events underlying HH/GLI-regulated cell fate determination and tumor growth. In this article, we describe the use...
5.
Hesse J, Jacak J, Kasper M, Regl G, Eichberger T, Winklmayr M, et al.
Genome Res
. 2006 Jul;
16(8):1041-5.
PMID: 16809670
We developed a microarray platform for PCR amplification-independent expression profiling of minute samples. A novel scanning system combined with specialized biochips enables detection down to individual fluorescent oligonucleotide molecules specifically...
6.
Eichberger T, Sander V, Schnidar H, Regl G, Kasper M, Schmid C, et al.
Genomics
. 2006 Jan;
87(5):616-32.
PMID: 16434164
The GLI transcription factors mediate the hedgehog signal in development and carcinogenesis. Basal cell carcinoma can be caused by overexpression of either GLI1 or GLI2. Though GLI1 and GLI2 have...
7.
Regl G, Kasper M, Schnidar H, Eichberger T, Neill G, Philpott M, et al.
Cancer Res
. 2004 Nov;
64(21):7724-31.
PMID: 15520176
Aberrant activation of the Hedgehog (HH)/GLI signaling pathway has been implicated in the development of basal cell carcinoma (BCC). The zinc finger transcription factors GLI1 and GLI2 are considered mediators...
8.
Ikram M, Neill G, Regl G, Eichberger T, Frischauf A, Aberger F, et al.
J Invest Dermatol
. 2004 Jun;
122(6):1503-9.
PMID: 15175043
Sonic hedgehog (Shh) binds to its receptor patched (PTCH), leading to the activation and repression of target genes via the GLI family of zinc-finger transcription factors. Deregulation of the Shh...
9.
FOXE1, a new transcriptional target of GLI2 is expressed in human epidermis and basal cell carcinoma
Eichberger T, Regl G, Ikram M, Neill G, Philpott M, Aberger F, et al.
J Invest Dermatol
. 2004 May;
122(5):1180-7.
PMID: 15140221
Sonic hedgehog (Hh) signaling plays a key role in epidermal development and skin cancer. Mutational inactivation of the tumor suppressor gene patched (PTCH) leads to constitutive activation of the Hh...
10.
Regl G, Kasper M, Schnidar H, Eichberger T, Neill G, Ikram M, et al.
Oncogene
. 2003 Dec;
23(6):1263-74.
PMID: 14691458
In stratified epidermis, activation of the Hh/Gli signal transduction pathway has been implicated in the control of cell proliferation and tumorigenesis. The zinc-finger transcription factor Gli2 has been identified as...