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Thomas E Angel

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Articles 28
Citations 846
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Recent Articles
11.
Schutzer S, Angel T, Liu T, Schepmoes A, Xie F, Bergquist J, et al.
PLoS One . 2013 Sep; 8(9):e66117. PMID: 24039694
The cause of multiple sclerosis (MS), its driving pathogenesis at the earliest stages, and what factors allow the first clinical attack to manifest remain unknown. Some imaging studies suggest gray...
12.
Price R, Peterson J, Fuchs D, Angel T, Zetterberg H, Hagberg L, et al.
J Neuroimmune Pharmacol . 2013 Aug; 8(5):1147-58. PMID: 23943280
Central nervous system (CNS) infection is a nearly universal facet of systemic HIV infection that varies in character and neurological consequences. While clinical staging and neuropsychological test performance have been...
13.
Aryal U, Callister S, Mishra S, Zhang X, Shutthanandan J, Angel T, et al.
Appl Environ Microbiol . 2012 Dec; 79(4):1070-7. PMID: 23204418
Cultures of the cyanobacterial genus Cyanothece have been shown to produce high levels of biohydrogen. These strains are diazotrophic and undergo pronounced diurnal cycles when grown under N(2)-fixing conditions in...
14.
Sadler N, Angel T, Lewis M, Pederson L, Chauvigne-Hines L, Wiedner S, et al.
PLoS One . 2012 Oct; 7(10):e47996. PMID: 23110155
High-fat diet (HFD) induced obesity and concomitant development of insulin resistance (IR) and type 2 diabetes mellitus have been linked to mitochondrial dysfunction. However, it is not clear whether mitochondrial...
15.
Hu Z, Browne E, Liu T, Angel T, Ho P, Chan E
J Proteome Res . 2012 Oct; 11(12):5903-13. PMID: 23078235
Identification of molecular mechanisms underlying early stage Alzheimer's disease (AD) is important for the development of new therapies against and diagnosis of AD. In this study, nontargeted metabonomics of TASTPM...
16.
Angel T, Jacobs J, Smith R, Pasternack M, Elias S, Gritsenko M, et al.
J Proteome Res . 2012 Aug; 11(10):4814-22. PMID: 22900834
During acute Lyme disease, bacteria can disseminate to the central nervous system (CNS), leading to the development of meningitis and other neurologic symptoms. Here we have analyzed pooled cerebrospinal fluid...
17.
Brown J, Ortiz G, Angel T, Jacobs J, Gritsenko M, Chan E, et al.
Mol Cell Proteomics . 2012 May; 11(9):605-18. PMID: 22580588
Morphine has long been known to have immunosuppressive properties in vivo, but the molecular and immunologic changes induced by it are incompletely understood. To explore how these changes interact with...
18.
Angel T, Aryal U, Hengel S, Baker E, Kelly R, Robinson E, et al.
Chem Soc Rev . 2012 Apr; 41(10):3912-28. PMID: 22498958
Mass spectrometry (MS)-based proteomics is emerging as a broadly effective means for identification, characterization, and quantification of proteins that are integral components of the processes essential for life. Characterization of...
19.
Angel T, Jacobs J, Spudich S, Gritsenko M, Fuchs D, Liegler T, et al.
Clin Proteomics . 2012 Mar; 9(1):3. PMID: 22433316
Background: Central nervous system (CNS) infection is a nearly universal feature of untreated systemic HIV infection with a clinical spectrum that ranges from chronic asymptomatic infection to severe cognitive and...
20.
Schutzer S, Angel T, Liu T, Schepmoes A, Clauss T, Adkins J, et al.
PLoS One . 2011 Mar; 6(2):e17287. PMID: 21383843
Background: Neurologic Post Treatment Lyme disease (nPTLS) and Chronic Fatigue (CFS) are syndromes of unknown etiology. They share features of fatigue and cognitive dysfunction, making it difficult to differentiate them....