Thomas Cailly
Overview
Explore the profile of Thomas Cailly including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
30
Citations
234
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Dubost E, McErlain H, Babin V, Sutherland A, Cailly T
J Org Chem
. 2020 May;
85(13):8300-8310.
PMID: 32369696
Organic compounds bearing radioisotopes of iodine are widely used for biological research, diagnostic imaging, and radiotherapy. Early reported synthetic methods for the incorporation of radioiodine have generally involved high temperature...
12.
Babin V, Tournier B, Davis A, Dubost E, Pigree G, Lohier J, et al.
Bioorg Chem
. 2020 Jan;
96:103582.
PMID: 31978687
A series of iodinated ligands for the SPECT imaging of 5-HT receptors was designed starting from the previously reported hit MR-26132. We focused on the modulation of the piperidine-containing lateral...
13.
Tournier B, Tsartsalis S, Rigaud D, Fossey C, Cailly T, Fabis F, et al.
Neurobiol Dis
. 2018 Sep;
121:95-105.
PMID: 30261283
The involvement of the 18kDa translocator protein (TSPO), a marker of neuroinflammation, in Alzheimer's disease (AD) remains controversial. In the present report, we used [I]-CLINDE, a SPECT TSPO radiotracer never...
14.
Dubost E, Babin V, Benoist F, Hebert A, Barbey P, Chollet C, et al.
Org Lett
. 2018 Sep;
20(19):6302-6305.
PMID: 30232893
The palladium-mediated C-H radio-iodination of arenes using sodium iodide as the primary isotopic source is reported and performed without chemical know-how in 30 min and applied to the synthesis of...
15.
Wilson T, Cailly T, Gouverneur V
Chem Soc Rev
. 2018 Aug;
47(18):6990-7005.
PMID: 30140795
Radiolabelled (bio)molecules have advanced many areas of science from fundamental biology to human health including applications in molecular imaging and more generally nuclear medicine. Today, the field of radiochemistry is...
16.
Wilson T, McSweeney G, Preshlock S, Verhoog S, Tredwell M, Cailly T, et al.
Chem Commun (Camb)
. 2016 Nov;
52(90):13277-13280.
PMID: 27775106
A general method for the copper mediated nucleophilic I-iodination of (hetero)aryl boronic esters and acids has been developed. The broad substrate scope of this radiosynthetic approach allows access to [I]DPA-713,...
17.
Preshlock S, Calderwood S, Verhoog S, Tredwell M, Huiban M, Hienzsch A, et al.
Chem Commun (Camb)
. 2016 Jun;
52(54):8361-4.
PMID: 27241832
[(18)F]FMTEB, [(18)F]FPEB, [(18)F]flumazenil, [(18)F]DAA1106, [(18)F]MFBG, [(18)F]FDOPA, [(18)F]FMT and [(18)F]FDA are prepared from the corresponding arylboronic esters and [(18)F]KF/K222 in the presence of Cu(OTf)2py4. The method was successfully applied using three...
18.
Lalut J, Tournier B, Cailly T, Lecoutey C, Corvaisier S, Davis A, et al.
Eur J Med Chem
. 2016 Apr;
116:90-101.
PMID: 27060761
Despite its implication in several physiological and pathological processes the serotonin subtype-4 receptor (5-HT4R) has seen limited effort for the development of radiolabeling agent especially concerning single photon emission computed...
19.
Lam B, Berhault Y, Stiebing S, Fossey C, Cailly T, Collot V, et al.
Chemistry
. 2016 Feb;
22(13):4440-6.
PMID: 26879134
A unique route to highly functionalized indazoles is described. A regioselective magnesiation at position 3 of 4-, 5-, 6- and 7-iodo-2-THP-indazoles (THP=tetrahydropyranyl) has been developed using TMPMgCl⋅LiCl (TMP=2,2,6,6-tetramethylpiperidyl). The obtained...
20.
Fresneau N, Dumas N, Tournier B, Fossey C, Ballandonne C, Lesnard A, et al.
Eur J Med Chem
. 2015 Mar;
94:386-96.
PMID: 25778994
With the aim to develop a suitable radiotracer for the brain imaging of the serotonin 4 receptor subtype (5-HT4R) using single photon emission computed tomography (SPECT), we synthesized and evaluated...