Thomas C Ferrante
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Explore the profile of Thomas C Ferrante including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
2224
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0
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Recent Articles
1.
Izadifar Z, Charrez B, Almeida M, Robben S, Pilobello K, van der Graaf-Mas J, et al.
Biosens Bioelectron
. 2024 Aug;
265:116683.
PMID: 39213819
Despite remarkable advances in Organ-on-a-chip (Organ Chip) microfluidic culture technology, recreating tissue-relevant physiological conditions, such as the region-specific oxygen concentrations, remains a formidable technical challenge, and analysis of tissue functions...
2.
Zeng Y, Young O, Wintersinger C, Anastassacos F, MacDonald J, Isinelli G, et al.
Nat Nanotechnol
. 2024 Mar;
19(7):1055-1065.
PMID: 38491184
Multivalent presentation of ligands often enhances receptor activation and downstream signalling. DNA origami offers a precise nanoscale spacing of ligands, a potentially useful feature for therapeutic nanoparticles. Here we use...
3.
Goyal G, Prabhala P, Mahajan G, Bausk B, Gilboa T, Xie L, et al.
Adv Sci (Weinh)
. 2022 Mar;
9(14):e2103241.
PMID: 35289122
Lymphoid follicles (LFs) are responsible for generation of adaptive immune responses in secondary lymphoid organs and form ectopically during chronic inflammation. A human model of ectopic LF formation will provide...
4.
de Puig H, Lee R, Najjar D, Tan X, Soeknsen L, Angenent-Mari N, et al.
Sci Adv
. 2021 Aug;
7(32).
PMID: 34362739
The COVID-19 pandemic highlights the need for diagnostics that can be rapidly adapted and deployed in a variety of settings. Several SARS-CoV-2 variants have shown worrisome effects on vaccine and...
5.
Benam K, Novak R, Ferrante T, Choe Y, Ingber D
Nat Protoc
. 2020 Jan;
15(2):183-206.
PMID: 31925401
Exposure of lung tissues to cigarette smoke is a major cause of human disease and death worldwide. Unfortunately, adequate model systems that can reliably recapitulate disease biogenesis in vitro, including...
6.
Sontheimer-Phelps A, Chou D, Tovaglieri A, Ferrante T, Duckworth T, Fadel C, et al.
Cell Mol Gastroenterol Hepatol
. 2019 Nov;
9(3):507-526.
PMID: 31778828
Background & Aims: The mucus layer in the human colon protects against commensal bacteria and pathogens, and defects in its unique bilayered structure contribute to intestinal disorders, such as ulcerative...
7.
Stark J, Huang A, Nguyen P, Dubner R, Hsu K, Ferrante T, et al.
Sci Adv
. 2018 Aug;
4(8):eaat5107.
PMID: 30083609
Synthetic biology offers opportunities for experiential educational activities at the intersection of the life sciences, engineering, and design. However, implementation of hands-on biology activities in classrooms is challenging because of...
8.
Jalili-Firoozinezhad S, Prantil-Baun R, Jiang A, Potla R, Mammoto T, Weaver J, et al.
Cell Death Dis
. 2018 Feb;
9(2):223.
PMID: 29445080
Studies on human intestinal injury induced by acute exposure to γ-radiation commonly rely on use of animal models because culture systems do not faithfully mimic human intestinal physiology. Here we...
9.
Musah S, Mammoto A, Ferrante T, Jeanty S, Hirano-Kobayashi M, Mammoto T, et al.
Nat Biomed Eng
. 2017 Oct;
1.
PMID: 29038743
An model of the human kidney glomerulus - the major site of blood filtration - could facilitate drug discovery and illuminate kidney-disease mechanisms. Microfluidic organ-on-a-chip technology has been used to...
10.
Benam K, Mazur M, Choe Y, Ferrante T, Novak R, Ingber D
Methods Mol Biol
. 2017 Jun;
1612:345-365.
PMID: 28634955
Organs-on-chips are microfluidic cell culture devices created using microchip manufacturing techniques that contain hollow microchannels lined by living cells, which recreate specialized tissue-tissue interfaces, physical microenvironments, and vascular perfusion necessary...