Thomas C Beadnell
Overview
Explore the profile of Thomas C Beadnell including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
718
Followers
0
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Recent Articles
1.
Beadnell T, Jasti S, Wang R, Davis B, Litwin V
Int J Mol Sci
. 2024 Oct;
25(19).
PMID: 39408593
Monitoring chimeric antigen redirected (CAR) T-cells post-infusion in clinical trials is a specialized application of flow cytometry. Unlike the CAR T-cell monitoring for individual patients conducted in clinical laboratories, the...
2.
Bolf E, Beadnell T, Rose M, DAlessandro A, Nemkov T, Hansen K, et al.
Cells
. 2023 Jul;
12(10).
PMID: 37408209
Thyroid cancer is the most common endocrine neoplasm, and despite its overall high survival rate, patients with metastatic disease or tumors that resist radioactive iodine experience a significantly worse prognosis....
3.
Nathanson S, Detmar M, Padera T, Yates L, Welch D, Beadnell T, et al.
Clin Exp Metastasis
. 2021 May;
39(1):117-137.
PMID: 33950409
Invasive breast cancer tends to metastasize to lymph nodes and systemic sites. The management of metastasis has evolved by focusing on controlling the growth of the disease in the breast/chest...
4.
Scheid A, Beadnell T, Welch D
Br J Cancer
. 2020 Nov;
124(1):124-135.
PMID: 33144695
Although mitochondrial contributions to cancer have been recognised for approximately a century, given that mitochondrial DNA (mtDNA) is dwarfed by the size of the nuclear genome (nDNA), nuclear genetics has...
5.
Young E, Manley S, Beadnell T, Shearin A, Sasaki K, Zimmerman R, et al.
Br J Cancer
. 2020 Oct;
124(1):166-175.
PMID: 33024269
Background: Previously, we identified ITIH5 as a suppressor of pancreatic ductal adenocarcinoma (PDAC) metastasis in experimental models. Expression of ITIH5 correlated with decreased cell motility, invasion and metastasis without significant...
6.
Brinker A, Vivian C, Beadnell T, Koestler D, Teoh S, Lunt S, et al.
Cancer Res
. 2019 Dec;
80(5):1118-1129.
PMID: 31848195
Mitochondria contribute to tumor growth through multiple metabolic pathways, regulation of extracellular pH, calcium signaling, and apoptosis. Using the Mitochondrial Nuclear Exchange (MNX) mouse models, which pair nuclear genomes with...
7.
Scheid A, Beadnell T, Welch D
Adv Cancer Res
. 2019 Mar;
142:63-105.
PMID: 30885364
The role of genetics in cancer has been recognized for centuries, but most studies elucidating genetic contributions to cancer have understandably focused on the nuclear genome. Mitochondrial contributions to cancer...
8.
Beadnell T, Scheid A, Vivian C, Welch D
Cancer Metastasis Rev
. 2018 Dec;
37(4):615-632.
PMID: 30542781
Mitochondrial DNA (mtDNA) encodes for only a fraction of the proteins that are encoded within the nucleus, and therefore has typically been regarded as a lesser player in cancer biology...
9.
10.
Beadnell T, Nassar K, Rose M, Clark E, Danysh B, Hofmann M, et al.
Oncogenesis
. 2018 Mar;
7(2):23.
PMID: 29487290
Advanced stages of papillary and anaplastic thyroid cancer continue to be plagued by a dismal prognosis, which is a result of limited effective therapies for these cancers. Due to the...