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Thomas Bovbjerg Rasmussen

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Articles 12
Citations 1069
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Recent Articles
1.
Hvid H, Jensen S, Witgen B, Fledelius C, Damgaard J, Pyke C, et al.
Digestion . 2016 Dec; 94(4):199-214. PMID: 27931035
Background/aims: In contrast to streptozotocin (STZ)-induced rodent models of diabetes, there are no thorough characterizations of the intestinal phenotype and the underlying changes in the global gene-expression of genetic models...
2.
Jakobsen T, van Gennip M, Phipps R, Shanmugham M, Christensen L, Alhede M, et al.
Antimicrob Agents Chemother . 2012 Feb; 56(5):2314-25. PMID: 22314537
In relation to emerging multiresistant bacteria, development of antimicrobials and new treatment strategies of infections should be expected to become a high-priority research area. Quorum sensing (QS), a communication system...
3.
Eng C, Thibessard A, Danielsen M, Rasmussen T, Mari J, Leblond P
Arch Microbiol . 2011 Jan; 193(4):287-97. PMID: 21234750
A combination of gene loss and acquisition through horizontal gene transfer (HGT) is thought to drive Streptococcus thermophilus adaptation to its niche, i.e. milk. In this study, we describe an...
4.
Alhede M, Bjarnsholt T, Jensen P, Phipps R, Moser C, Christophersen L, et al.
Microbiology (Reading) . 2009 Aug; 155(Pt 11):3500-3508. PMID: 19643762
Polymorphonuclear neutrophilic leukocytes (PMNs) play a central role in innate immunity, where they dominate the response to infections, in particular in the cystic fibrosis lung. PMNs are phagocytic cells that...
5.
Rasmussen T, Danielsen M, Valina O, Garrigues C, Johansen E, Pedersen M
Appl Environ Microbiol . 2008 Jun; 74(15):4703-10. PMID: 18539806
A DNA microarray platform based on 2,200 genes from publicly available sequences was designed for Streptococcus thermophilus. We determined how single-nucleotide polymorphisms in the 65- to 75-mer oligonucleotide probe sequences...
6.
Skindersoe M, Ettinger-Epstein P, Rasmussen T, Bjarnsholt T, de Nys R, Givskov M
Mar Biotechnol (NY) . 2007 Oct; 10(1):56-63. PMID: 17952508
With the global emergence of multiresistant bacteria there is an increasing demand for development of new treatments to combat pathogens. Bacterial cell-cell communication [quorum sensing (QS)] regulates expression of virulence...
7.
Hoffmann N, Lee B, Hentzer M, Rasmussen T, Song Z, Krogh Johansen H, et al.
Antimicrob Agents Chemother . 2007 Jul; 51(10):3677-87. PMID: 17620382
The consequences of O-acetylated alginate-producing Pseudomonas aeruginosa biofilms in the lungs of chronically infected cystic fibrosis (CF) patients are tolerance to both antibiotic treatments and effects on the innate and...
8.
Rasmussen T, Skindersoe M, Bjarnsholt T, Phipps R, Christensen K, Jensen P, et al.
Microbiology (Reading) . 2005 May; 151(Pt 5):1325-1340. PMID: 15870443
Quorum sensing (QS) communication systems are thought to afford bacteria with a mechanism to strategically cause disease. One example is Pseudomonas aeruginosa, which infects immunocompromised individuals such as cystic fibrosis...
9.
Hoffmann N, Rasmussen T, Jensen P, Stub C, Hentzer M, Molin S, et al.
Infect Immun . 2005 Mar; 73(4):2504-14. PMID: 15784597
Pseudomonas aeruginosa causes a chronic infection in the lungs of cystic fibrosis (CF) patients by establishing an alginate-containing biofilm. The infection has been studied in several animal models; however, most...
10.
Rasmussen T, Bjarnsholt T, Skindersoe M, Hentzer M, Kristoffersen P, Kote M, et al.
J Bacteriol . 2005 Feb; 187(5):1799-814. PMID: 15716452
With the widespread appearance of antibiotic-resistant bacteria, there is an increasing demand for novel strategies to control infectious diseases. Furthermore, it has become apparent that the bacterial life style also...