Jens Bo Andersen
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Explore the profile of Jens Bo Andersen including associated specialties, affiliations and a list of published articles.
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32
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1665
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Recent Articles
1.
Andersen J, Rybtke M, Tolker-Nielsen T
Biofilm
. 2024 Jul;
8:100207.
PMID: 39021701
The crystal violet microtiter plate biofilm assay is often used to compare the amount of biofilm formed by a mutant versus wild-type or a compound-treated biofilm versus the non-treatment control....
2.
Jansen C, Grier K, Andersen J, Hultqvist L, Nilsson M, Moser C, et al.
Int J Mol Sci
. 2024 Jun;
25(12).
PMID: 38928443
This paper presents the work performed to transition a lab-scale synthesis (1 g) to a large-scale (400 g) synthesis of the 3-5-diamino-1H-Pyrazole Disperazol, a new pharmaceutical for treatment of antibiotic-resistant...
3.
Hultqvist L, Andersen J, Nilsson C, Jansen C, Rybtke M, Jakobsen T, et al.
Antimicrob Agents Chemother
. 2024 May;
68(6):e0148123.
PMID: 38717093
Persistent urinary tract infections (UTIs) in hospitalized patients constitute an important medical problem. It is estimated that 75% of nosocomial UTIs are associated with urinary tract catheters with being a...
4.
Kristensen R, Andersen J, Rybtke M, Jansen C, Fritz B, Kiilerich R, et al.
Antimicrob Agents Chemother
. 2024 Jan;
68(2):e0138723.
PMID: 38189278
The cell-to-cell communication system quorum sensing (QS), used by various pathogenic bacteria to synchronize gene expression and increase host invasion potentials, is studied as a potential target for persistent infection...
5.
Gur M, Erdmann J, Will A, Liang Z, Andersen J, Tolker-Nielsen T, et al.
FEMS Microbes
. 2023 Aug;
4:xtad012.
PMID: 37564278
In the type strain PA14, 40 genes are known to encode for diguanylate cyclases (DGCs) and/or phosphodiesterases (PDEs), which modulate the intracellular pool of the nucleotide second messenger c-di-GMP. While...
6.
Liang Z, Nilsson M, Kragh K, Hedal I, Alcacer-Almansa J, Kiilerich R, et al.
Front Microbiol
. 2023 Jun;
14:1187708.
PMID: 37333638
The bacterium is involved in chronic infections of cystic fibrosis lungs and chronic wounds. In these infections the bacteria are present as aggregates suspended in host secretions. During the course...
7.
Manner C, Teixeira R, Saha D, Kaczmarczyk A, Zemp R, Wyss F, et al.
Nat Microbiol
. 2023 Jun;
8(8):1520-1533.
PMID: 37291227
Efficient colonization of mucosal surfaces is essential for opportunistic pathogens like Pseudomonas aeruginosa, but how bacteria collectively and individually adapt to optimize adherence, virulence and dispersal is largely unclear. Here...
8.
Liang Z, Rybtke M, Kragh K, Johnson O, Schicketanz M, Zhang Y, et al.
Microbiol Spectr
. 2022 Jul;
10(4):e0067522.
PMID: 35862969
Overproduction of the exopolysaccharide alginate contributes to the pathogenicity and antibiotic tolerance of Pseudomonas aeruginosa in chronic infections. The second messenger, c-di-GMP, is a positive regulator of the production of...
9.
Andersen J, Hultqvist L, Jansen C, Jakobsen T, Nilsson M, Rybtke M, et al.
NPJ Biofilms Microbiomes
. 2021 Jul;
7(1):59.
PMID: 34244523
Microbial biofilms are involved in a number of infections that cannot be cured, as microbes in biofilms resist host immune defenses and antibiotic therapies. With no strict biofilm-antibiotic in the...
10.
Andersen J, Kragh K, Hultqvist L, Rybtke M, Nilsson M, Jakobsen T, et al.
Antimicrob Agents Chemother
. 2021 Jan;
65(4).
PMID: 33495218
A decade of research has shown that the molecule c-di-GMP functions as a central second messenger in many bacteria. A high level of c-di-GMP is associated with biofilm formation, whereas...