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Thomas B Clarkson

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Articles 81
Citations 1175
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Recent Articles
1.
Vail K, Bourland J, Dugan G, Chen B, Clarkson T, Cline J, et al.
Toxicol Pathol . 2024 Sep; 52(6):308-318. PMID: 39254136
Cardiac exposure to ionizing radiation can damage both the microvasculature and coronary arteries, as well as increase the long-term risk of heart disease, myocardial fibrosis, and conduction abnormalities. Therapeutic agents...
2.
Silverstein-Metzler M, Frye B, Justice J, Clarkson T, Appt S, Carr J, et al.
Psychoneuroendocrinology . 2022 Mar; 139:105706. PMID: 35259592
Chronic psychosocial stress is associated with increased risk of many chronic diseases including type 2 diabetes mellitus. However, it is difficult to establish a causal relationship between stress and diabetes...
3.
Michalson K, Groban L, Howard T, Shively C, Sophonsritsuk A, Appt S, et al.
J Am Heart Assoc . 2018 Dec; 7(21):e009769. PMID: 30571375
Background Left ventricular ( LV ) diastolic dysfunction often precedes heart failure with preserved ejection fraction, the dominant form of heart failure in postmenopausal women. The objective of this study...
4.
Clarkson T
Menopause . 2018 Oct; 25(11):1262-1274. PMID: 30358722
Premenopausal Years: Premenopausal atherosclerosis progression seems to be an important determinant of postmenopausal atherosclerosis and thus the risk for CHD. Clearly, plasma lipids/lipoproteins influence this progression; however, estradiol deficiency seems...
5.
Shively C, Register T, Appt S, Clarkson T, Uberseder B, Clear K, et al.
Cell Rep . 2018 Oct; 25(1):47-56.e3. PMID: 30282037
Recent identification of a mammary gland-specific microbiome led to studies investigating bacteria populations in breast cancer. Malignant breast tumors have lower Lactobacillus abundance compared with benign lesions, implicating Lactobacillus as...
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Justice J, Silverstein-Metzler M, Uberseder B, Appt S, Clarkson T, Register T, et al.
Geroscience . 2017 Oct; 39(5-6):585-600. PMID: 29080976
Depression is the most common mental health problem in aging persons and is a leading risk factor for physical disability, especially in women. Though antidepressant drugs such as serotonin reuptake...
8.
Silverstein-Metzler M, Shively C, Clarkson T, Appt S, Carr J, Kritchevsky S, et al.
Psychoneuroendocrinology . 2016 Mar; 68:29-38. PMID: 26939086
Selective serotonin reuptake inhibitor (SSRI) antidepressants are widely prescribed for depression and other disorders. SSRIs have become one of the most commonly used drugs in the United States, particularly by...
9.
McCurdy R, Jiang X, Clarkson T, Nudy M, Schnatz P
Menopause . 2016 Feb; 23(5):481-7. PMID: 26886883
Objective: To analyze vitamin D3 plasma concentrations among monkeys randomized to oral conjugated equine estrogen (CEE) versus control and the association with coronary artery atherosclerosis (CAA). Methods: Surgically postmenopausal monkeys...
10.
Chittoor G, Pajewski N, Saroja Voruganti V, Comuzzie A, Clarkson T, Nudy M, et al.
Am J Phys Anthropol . 2015 Dec; 159(4):639-45. PMID: 26708407
Objectives: The two objectives of the current study were to: 1) investigate the genetic contributions to variations in serum vitamin D concentrations under two dietary conditions (a standard monkey biscuit...