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» Authors » Thirupandiyur S Udayakumar

Thirupandiyur S Udayakumar

Explore the profile of Thirupandiyur S Udayakumar including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 17
Citations 239
Followers 0
Related Specialties
Oncology
Radiology
Cell Biology
Top 10 Co-Authors
Alan Pollack
Yidong Yang
Junwei Shi
Nesrin Dogan
Raymond B Nagle
Radka Stoyanova
Keying Xu
G Timothy Bowden
Mansoor M Ahmed
Paul Hachem
Published In
Int J Radiat Oncol Biol Phys
Med Phys
Mol Cancer Res
Neoplasia
Mol Carcinog
Affiliations
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Recent Articles
11.
Interaction of HIF-1α and Notch3 Is Required for the Expression of Carbonic Anhydrase 9 in Breast Carcinoma Cells
Shareef M, Udayakumar T, Sinha V, Saleem S, Griggs W
Genes Cancer . 2014 Jan; 4(11-12):513-23. PMID: 24386511
Expression of carbonic anhydrase 9 (CA9) is associated with poor prognosis and increased tumor aggressiveness and does not always correlate with HIF-1α expression. Presently, we analyzed the regulation of CA9...
12.
Adenovirus E2F1 overexpression sensitizes LNCaP and PC3 prostate tumor cells to radiation in vivo
Udayakumar T, Stoyanova R, Hachem P, Ahmed M, Pollack A
Int J Radiat Oncol Biol Phys . 2011 Jan; 79(2):549-58. PMID: 21195876
Purpose: We previously showed that E2F1 overexpression radiosensitizes prostate cancer cells in vitro. Here, we demonstrate the radiosensitization efficacy of adenovirus (Ad)-E2F1 infection in growing (orthotopic) LNCaP and (subcutaneous) PC3...
13.
Antisense MDM2 enhances E2F1-induced apoptosis and the combination sensitizes androgen-sensitive [corrected] and androgen-insensitive [corrected] prostate cancer cells to radiation
Udayakumar T, Hachem P, Ahmed M, Agrawal S, Pollack A
Mol Cancer Res . 2008 Nov; 6(11):1742-54. PMID: 19010821
We have previously shown in separate studies that MDM2 knockdown via antisense MDM2 (AS-MDM2) and E2F1 overexpression via adenoviral-mediated E2F1 (Ad-E2F1) sensitized prostate cancer cells to radiation. Because E2F1 and...
14.
Pharmacological inhibition of FGF receptor signaling inhibits LNCaP prostate tumor growth, promatrilysin, and PSA expression
Udayakumar T, Bair E, Nagle R, Timothy Bowden G
Mol Carcinog . 2003 Sep; 38(2):70-7. PMID: 14502646
Previously we have shown that the matrix metalloproteinase matrilysin (MMP-7) is overexpressed in human prostate cancers compared with normal epithelium. However, the mechanism for this overexpression is not understood. Human...
15.
Membrane type-1-matrix metalloproteinase expressed by prostate carcinoma cells cleaves human laminin-5 beta3 chain and induces cell migration
Udayakumar T, Chen M, Bair E, Von Bredow D, Cress A, Nagle R, et al.
Cancer Res . 2003 May; 63(9):2292-9. PMID: 12727852
Degradation of the extracellular matrix by proteolytic enzymes is a central aspect of physiological and pathologic tissue-remodeling processes such as trophoblastic implantation, wound healing, and tumor invasion. We have hypothesized...
16.
Androgens block interleukin-1 beta-induced promatrilysin expression in prostate carcinoma cells
Stratton M, Greenstein B, Udayakumar T, Nagle R, Timothy Bowden G
Prostate . 2002 Sep; 53(1):1-8. PMID: 12210475
Background: We have shown previously that interleukin (IL) -1 beta- and IL-6-induced promatrilysin expression is mediated by an indirect pathway that requires NF kappa B-dependent synthesis of IL-6 and STAT3...
17.
Fibroblast growth factor-1 induced promatrilysin expression through the activation of extracellular-regulated kinases and STAT3
Udayakumar T, Stratton M, Nagle R, Bowden G
Neoplasia . 2002 Apr; 4(1):60-7. PMID: 11922392
The MMP, matrilysin (MMP-7), has been shown to be overexpressed in prostate cancer cells and to increase prostate cancer cell invasion. Prostate stromal fibroblasts secrete factor(s), including fibroblast growth factor-1...