Raymond B Nagle
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Explore the profile of Raymond B Nagle including associated specialties, affiliations and a list of published articles.
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72
Citations
1386
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Recent Articles
1.
Marr K, Gard J, Harryman W, Keeswood E, Paxson A, Wolgemuth C, et al.
Biophys J
. 2023 Sep;
122(21):4194-4206.
PMID: 37766428
Bladder, colon, gastric, prostate, and uterine cancers originate in organs surrounded by laminin-coated smooth muscle. In human prostate cancer, tumors that are organ confined, without extracapsular extension through muscle, have...
2.
Harryman W, Marr K, Hernandez-Cortes D, Nagle R, Garcia J, Cress A
Cancer Metastasis Rev
. 2021 Jan;
40(1):205-219.
PMID: 33398621
Smooth muscle is found around organs in the digestive, respiratory, and reproductive tracts. Cancers arising in the bladder, prostate, stomach, colon, and other sites progress from low-risk disease to high-risk,...
3.
Harryman W, Warfel N, Nagle R, Cress A
Adv Exp Med Biol
. 2020 Jan;
1210:149-170.
PMID: 31900909
Localized prostate cancer (confined to the gland) generally is considered curable, with nearly a 100% 5-year-survival rate. When the tumor escapes the prostate capsule, leading to metastasis, there is a...
4.
Hinton J, Dvorak K, Roberts E, French W, Grubbs J, Cress A, et al.
Methods Protoc
. 2019 Nov;
2(4).
PMID: 31731599
Archived Hematoxylin and Eosin (H&E) stained pathology slides are routinely stored to index formalin-fixed paraffin-embedded (FFPE) sample tissue blocks. FFPE blocks are clinically annotated human tumor specimens that can be...
5.
Chen H, Sells E, Pandey R, Abril E, Hsu C, Krouse R, et al.
Oncotarget
. 2019 Nov;
10(58):6062-6078.
PMID: 31692974
Kallikrein-related peptidase 6 (KLK6) overexpression is commonly observed in primary tumors of colorectal cancer (CRC) patients and has been associated with tumor aggressiveness, metastasis, and poor prognosis. We previously established...
6.
Wang M, Nagle R, Knudsen B, Cress A, Rogers G
Oncogene
. 2019 Sep;
39(2):399-413.
PMID: 31477840
Localized, nonindolent prostate cancer (PCa) is characterized by large-scale genomic rearrangements, aneuploidy, chromothripsis, and other forms of chromosomal instability (CIN), yet how this occurs remains unclear. A well-established mechanism of...
7.
Rubenstein C, Gard J, Wang M, McGrath J, Ingabire N, Hinton J, et al.
Cancer Res
. 2019 Jul;
79(18):4703-4714.
PMID: 31337652
Human prostate cancer confined to the gland is indolent (low-risk), but tumors outside the capsule are aggressive (high-risk). Extracapsular extension requires invasion within and through a smooth muscle-structured environment. Because...
8.
Wang M, Hinton J, Gard J, Garcia J, Knudsen B, Nagle R, et al.
Mol Biol Cell
. 2019 Mar;
30(7):838-850.
PMID: 30865564
Integrin α6β4 is an essential, dynamic adhesion receptor for laminin 332 found on epithelial cells, required for formation of strong cell-extracellular matrix (ECM) adhesion and induced migration, and coordinated by...
9.
Wang M, Knudsen B, Nagle R, Rogers G, Cress A
Mol Biol Cell
. 2019 Jan;
30(7):811-819.
PMID: 30699045
Centrosome abnormalities are emerging hallmarks of cancer. The overproduction of centrosomes (known as centrosome amplification) has been reported in a variety of cancers and is currently being explored as a...
10.
Nagle R, Schmidt B
Zookeys
. 2018 Oct;
(788):69-77.
PMID: 30337824
is described from southeastern Arizona. Although superficially similar to species of Grote, structural and molecular variation shows it to be most closely related to (Cassino). Adults, genitalic structure, eggs, and...