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Thierry Sengstag

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Citations 6201
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Recent Articles
1.
Martani A, Genevieve L, Wangmo T, Maurer J, Crameri K, Erard F, et al.
Digit Health . 2023 Apr; 9:20552076231169826. PMID: 37113255
Introduction: Ensuring that the health data infrastructure and governance permits an efficient secondary use of data for research is a policy priority for many countries. Switzerland is no exception and...
2.
Goers R, Schmid D, Jaggi V, Paioni P, Okoniewski M, Parker A, et al.
CPT Pharmacometrics Syst Pharmacol . 2021 Nov; 10(12):1578-1587. PMID: 34729953
Clinical trials have been performed mainly in adults and accordingly the necessary information is lacking for pediatric patients, especially regarding dosage recommendation for approved drugs. This gap in information could...
3.
Schmid D, Crameri K, Oesterle S, Rinn B, Sengstag T, Stockinger H
Stud Health Technol Inform . 2020 Jun; 270:1170-1174. PMID: 32570566
The BioMedIT project is funded by the Swiss government as an integral part of the Swiss Personalized Health Network (SPHN), aiming to provide researchers with access to a secure, powerful...
4.
Wilkinson M, Dumontier M, Aalbersberg I, Appleton G, Axton M, Baak A, et al.
Sci Data . 2019 Mar; 6(1):6. PMID: 30890711
No abstract available.
5.
Egli T, Vukojevic V, Sengstag T, Jacquot M, Cabezon R, Coynel D, et al.
Sci Rep . 2017 Oct; 7(1):13669. PMID: 29057891
Studies assessing the existence and magnitude of epistatic effects on complex human traits provide inconclusive results. The study of such effects is complicated by considerable increase in computational burden, model...
6.
Noguchi S, Arakawa T, Fukuda S, Furuno M, Hasegawa A, Hori F, et al.
Sci Data . 2017 Aug; 4:170112. PMID: 28850106
In the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGE (Cap Analysis of...
7.
Auffray C, Balling R, Barroso I, Bencze L, Benson M, Bergeron J, et al.
Genome Med . 2016 Nov; 8(1):118. PMID: 27821178
No abstract available.
8.
Auffray C, Balling R, Barroso I, Bencze L, Benson M, Bergeron J, et al.
Genome Med . 2016 Jun; 8(1):71. PMID: 27338147
Medicine and healthcare are undergoing profound changes. Whole-genome sequencing and high-resolution imaging technologies are key drivers of this rapid and crucial transformation. Technological innovation combined with automation and miniaturization has...
9.
Wilkinson M, Dumontier M, Aalbersberg I, Appleton G, Axton M, Baak A, et al.
Sci Data . 2016 Mar; 3:160018. PMID: 26978244
There is an urgent need to improve the infrastructure supporting the reuse of scholarly data. A diverse set of stakeholders-representing academia, industry, funding agencies, and scholarly publishers-have come together to...
10.
Bohne A, Sengstag T, Salzburger W
Genome Biol Evol . 2014 Nov; 6(9):2567-85. PMID: 25364805
Males and females of the same species differ largely in gene expression, which accounts for most of the morphological and physiological differences and sex-specific phenotypes. Here, we analyzed sex-specific gene...