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Thibault Gendron

Explore the profile of Thibault Gendron including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 268
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Recent Articles
1.
Farooq R, Gendron T, Edwards R, Witney T
EJNMMI Radiopharm Chem . 2025 Jan; 10(1):2. PMID: 39821860
Background: (S)-4-(3-F-Fluoropropyl)-ʟ-glutamic acid ([F]FSPG) is a positron emission tomography radiotracer used to image system x, an antiporter that is upregulated in several cancers. Not only does imaging system x with...
2.
Paty L, Degueldre S, Provost C, Schmitt C, Trump L, Fouque J, et al.
Front Chem . 2024 Jul; 12:1411312. PMID: 39076612
Gallium-68-labeled FAPI-46 has recently been proposed as a novel positron emission tomography imaging probe to diagnose and monitor a wide variety of cancers. Promising results from several ongoing clinical trials...
3.
Gendron T, Lanfranchi D, Wenzel N, Kessedjian H, Jannack B, Maes L, et al.
Molecules . 2024 Apr; 29(7). PMID: 38611899
2,6-Diaryl-4-tetrahydro-thiopyran-4-ones and corresponding sulfoxide and sulfone derivatives were designed to lower the major toxicity of their parent anti-kinetoplatidal diarylideneacetones through a prodrug effect. Novel diastereoselective methodologies were developed and generalized...
4.
Pacelli A, Zarrad F, Warnier C, Gendron T, Otabashi M, Vriamont C, et al.
Pharmaceuticals (Basel) . 2023 Jul; 16(7). PMID: 37513966
Corentin Warnier, Thibault Gendron, Muhammad Otabashi, Charles Vriamont and Alex Jackson were not included as authors in the original publication [...].
5.
Gendron T, Destro G, Straathof N, Sap J, Guibbal F, Vriamont C, et al.
EJNMMI Radiopharm Chem . 2022 Mar; 7(1):5. PMID: 35306596
Background: Flumazenil (FMZ) is a functionally silent imidazobenzodiazepine which binds to the benzodiazepine binding site of approximately 75% of the brain γ-aminobutyric acid-A receptors (GABARs). Positron Emission Tomography (PET) imaging...
6.
Sander K, Gendron T, Cybulska K, Sirindil F, Zhou J, Kalber T, et al.
J Med Chem . 2021 Jun; 64(13):9321-9329. PMID: 34137616
The purpose of this study was to synthesize a fluorine-18 labeled, highly selective aldosterone synthase (CYP11B2) inhibitor, [F]AldoView, and to assess its potential for the detection of aldosterone-producing adenomas (APAs)...
7.
Gendron T, Pereira R, Abdi H, Witney T, Arstad E
Org Lett . 2019 Dec; 22(1):274-278. PMID: 31851521
Herein, we report that iron(II)/ammonium persulfate in aqueous acetonitrile mediates the Newman-Kwart rearrangement of -aryl carbamothioates. Electron-rich substrates react rapidly under moderate heating to afford the rearranged products in excellent...
8.
Glaser M, Rajkumar V, Diocou S, Gendron T, Yan R, Sin P, et al.
Sci Rep . 2019 Dec; 9(1):19299. PMID: 31848442
Induction of apoptosis is often necessary for successful cancer therapy, and the non-invasive monitoring of apoptosis post-therapy could assist in clinical decision making. Isatins are a class of compounds that...
9.
Bascunana P, Gendron T, Sander K, Jahreis I, Polyak A, Ross T, et al.
Epilepsia . 2019 Oct; 60(11):2325-2333. PMID: 31571210
Objective: Identification of patients at risk of developing epilepsy before the first spontaneous seizure may promote the development of preventive treatment providing opportunity to stop or slow down the disease....
10.
Greenwood H, McCormick P, Gendron T, Glaser M, Pereira R, Maddocks O, et al.
Clin Cancer Res . 2019 Jan; 25(8):2471-2482. PMID: 30651275
Purpose: Drug resistance is a major obstacle for the effective treatment of patients with high-grade serous ovarian cancer (HGSOC). Currently, there is no satisfactory way to identify patients with HGSOC...