Thibault Gendron
Overview
Explore the profile of Thibault Gendron including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
16
Citations
268
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0
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Recent Articles
11.
Pereira R, Gendron T, Sanghera C, Greenwood H, Newcombe J, McCormick P, et al.
Chemistry
. 2018 Dec;
25(9):2345-2351.
PMID: 30521138
Aldehyde dehydrogenases (ALDHs) catalyze the oxidation of aldehydes to carboxylic acids. Elevated ALDH expression in human cancers is linked to metastases and poor overall survival. Despite ALDH being a poor...
12.
McCormick P, Greenwood H, Glaser M, Maddocks O, Gendron T, Sander K, et al.
Cancer Res
. 2018 Nov;
79(4):853-863.
PMID: 30401715
The cell's endogenous antioxidant system is vital to maintenance of redox homeostasis. Despite its central role in normal and pathophysiology, no noninvasive tools exist to measure this system in patients....
13.
Gendron T, Sander K, Cybulska K, Benhamou L, Sin P, Khan A, et al.
J Am Chem Soc
. 2018 Aug;
140(35):11125-11132.
PMID: 30132661
Herein, we report a novel intramolecular ring-closing reaction of biaryl thioethers that give access to highly functionalized dibenzothiophene sulfonium salts under mild conditions. The resulting precursors react regioselectively with [F]fluoride...
14.
Viira B, Gendron T, Lanfranchi D, Cojean S, Horvath D, Marcou G, et al.
Molecules
. 2016 Jul;
21(7).
PMID: 27367660
Malaria is a parasitic tropical disease that kills around 600,000 patients every year. The emergence of resistant Plasmodium falciparum parasites to artemisinin-based combination therapies (ACTs) represents a significant public health...
15.
Sander K, Lashley T, Gami P, Gendron T, Lythgoe M, Rohrer J, et al.
Alzheimers Dement
. 2016 Feb;
12(11):1116-1124.
PMID: 26892233
Introduction: Aggregation of tau is a hallmark of many neurodegenerative diseases, and tau imaging with positron emission tomography (PET) may allow early diagnosis and treatment monitoring. We assessed binding of...
16.
Sander K, Galante E, Gendron T, Yiannaki E, Patel N, Kalber T, et al.
J Med Chem
. 2015 Jul;
58(15):6058-80.
PMID: 26161456
Increased activity of efflux transporters, e.g., P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP), at the blood-brain barrier is a pathological hallmark of many neurological diseases, and the resulting multiple...
17.
Sander K, Gendron T, Yiannaki E, Cybulska K, Kalber T, Lythgoe M, et al.
Sci Rep
. 2015 Apr;
5:9941.
PMID: 25898175
Positron emission tomography (PET) is unique in that it allows quantification of biochemical processes in vivo, but difficulties with preparing suitably labelled radiotracers limit its scientific and diagnostic applications. Aromatic...