Theodoros I Roumeliotis
Overview
Explore the profile of Theodoros I Roumeliotis including associated specialties, affiliations and a list of published articles.
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1110
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Recent Articles
1.
Rega C, Tsitsa I, Roumeliotis T, Krystkowiak I, Portillo M, Yu L, et al.
Nat Commun
. 2025 Mar;
16(1):2579.
PMID: 40089461
The cell cycle governs a precise series of molecular events, regulated by coordinated changes in protein and phosphorylation abundance, that culminates in the generation of two daughter cells. Here, we...
2.
Lane K, Harrod A, Wu L, Roumeliotis T, Feng H, Foo S, et al.
Nat Commun
. 2025 Feb;
16(1):1980.
PMID: 40011561
The specialised structure of the centromere is critical for effective chromosome segregation, but its repetitive nature makes it vulnerable to rearrangements. Centromere fragility can drive tumorigenesis, but protective mechanisms preventing...
3.
Stewart J, Krastev D, Brough R, Zatreanu D, Song F, Baxter J, et al.
Oncogene
. 2025 Feb;
44(9):618-629.
PMID: 39939726
Identification of ARID1A/ATR synthetic lethality led to ATR inhibitor phase II trials in ovarian clear cell carcinoma (OCCC), a cancer of unmet need. Using multiple CRISPR-Cas9 mutagenesis and interference screens,...
4.
Welti J, Bogdan D, Figueiredo I, Coleman I, Jimenez Vacas J, Liodaki K, et al.
Clin Cancer Res
. 2025 Jan;
PMID: 39787247
Purpose: Advanced prostate cancer (PCa) is invariably fatal with the androgen receptor (AR) being a major therapeutic target. AR signaling inhibitors have improved overall survival for men with advanced PCa,...
5.
Hoenger Ramazanova R, Roumeliotis T, Wright J, Choudhary J
J Proteome Res
. 2024 Oct;
23(11):5209-5220.
PMID: 39422127
Integrating cross-linking mass spectrometry (XL-MS) into structural biology workflows provides valuable information about the spatial arrangement of amino acid stretches, which can guide elucidation of protein assembly architecture. Additionally, the...
6.
Lau R, Yu L, Roumeliotis T, Stewart A, Pickard L, Riisanes R, et al.
J Proteomics
. 2024 Sep;
309:105306.
PMID: 39243748
No abstract available.
7.
Cirillo L, Young R, Veerapathiran S, Roberti A, Martin M, Abubacar A, et al.
EMBO J
. 2024 Aug;
43(19):4324-4355.
PMID: 39143240
The proper control of mitosis depends on the ubiquitin-mediated degradation of the right mitotic regulator at the right time. This is effected by the Anaphase Promoting Complex/Cyclosome (APC/C) ubiquitin ligase...
8.
Klein P, Petric Howe M, Harley J, Crook H, Esteban Serna S, Roumeliotis T, et al.
Nat Commun
. 2024 Jun;
15(1):4819.
PMID: 38844464
Neuronal differentiation requires building a complex intracellular architecture, and therefore the coordinated regulation of defined sets of genes. RNA-binding proteins (RBPs) play a key role in this regulation. However, while...
9.
Badja C, Momen S, Koh G, Boushaki S, Roumeliotis T, Kozik Z, et al.
Cell Rep
. 2024 May;
43(6):114243.
PMID: 38805398
Xeroderma pigmentosum (XP) is caused by defective nucleotide excision repair of DNA damage. This results in hypersensitivity to ultraviolet light and increased skin cancer risk, as sunlight-induced photoproducts remain unrepaired....
10.
Mannion J, Gifford V, Bellenie B, Fernando W, Garcia L, Wilson R, et al.
Immunity
. 2024 May;
57(7):1514-1532.e15.
PMID: 38788712
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) functions as a critical stress sentinel that coordinates cell survival, inflammation, and immunogenic cell death (ICD). Although the catalytic function of RIPK1 is required to...