Theodore Alexandrov
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Explore the profile of Theodore Alexandrov including associated specialties, affiliations and a list of published articles.
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111
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5349
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Recent Articles
1.
Wadie B, Stuart L, Rath C, Drotleff B, Mamedov S, Alexandrov T
Nat Commun
. 2024 Oct;
15(1):9110.
PMID: 39438443
Imaging mass spectrometry is a powerful technology enabling spatial metabolomics, yet metabolites can be assigned only to a fraction of the data generated. METASPACE-ML is a machine learning-based approach addressing...
2.
Dekina S, Alexandrov T, Drotleff B
Metabolomics
. 2024 Oct;
20(6):114.
PMID: 39397202
Introduction: Over the past two decades, liquid chromatography-mass spectrometry (LC-MS)-based metabolomics has experienced significant growth, playing a crucial role in various scientific disciplines. However, despite these advance-ments, metabolite identification (MetID)...
3.
Buglakova E, Ekelof M, Schwaiger-Haber M, Schlicker L, Molenaar M, Shahraz M, et al.
Nat Metab
. 2024 Sep;
6(9):1695-1711.
PMID: 39251875
While heterogeneity is a key feature of cancer, understanding metabolic heterogeneity at the single-cell level remains a challenge. Here we present C-SpaceM, a method for spatial single-cell isotope tracing that...
4.
Li X, Gandara L, Ekelof M, Richter K, Alexandrov T, Crocker J
Nat Commun
. 2024 May;
15(1):4551.
PMID: 38811562
Although the effects of genetic and environmental perturbations on multicellular organisms are rarely restricted to single phenotypic layers, our current understanding of how developmental programs react to these challenges remains...
5.
Velickovic D, Shapiro J, Parikh S, Rovin B, Toto R, Vazquez M, et al.
J Am Soc Nephrol
. 2024 May;
PMID: 38771634
Background: Diabetes is expected to directly impact renal glycosylation, yet to date, there has not been a comprehensive evaluation of alterations in N-glycan composition in the glomeruli of patients with...
6.
Cosgrove J, Marcais A, Hartmann F, Bergthaler A, Zanoni I, Corrado M, et al.
Nat Metab
. 2024 Apr;
6(5):779-782.
PMID: 38605184
No abstract available.
7.
Buglakova E, Ekelof M, Schwaiger-Haber M, Schlicker L, Molenaar M, Mohammed S, et al.
bioRxiv
. 2024 Mar;
PMID: 38464218
Metabolism has emerged as a key factor in homeostasis and disease including cancer. Yet, little is known about the heterogeneity of metabolic activity of cancer cells due to the lack...
8.
van der Weijden V, Stotzel M, Iyer D, Fauler B, Gralinska E, Shahraz M, et al.
Nat Cell Biol
. 2024 Jan;
26(2):181-193.
PMID: 38177284
Mammalian developmental timing is adjustable in vivo by preserving pre-implantation embryos in a dormant state called diapause. Inhibition of the growth regulator mTOR (mTORi) pauses mouse development in vitro, yet...
9.
Alexandrov T, Saez-Rodriguez J, Saka S
Mol Syst Biol
. 2023 Oct;
19(11):e10571.
PMID: 37842805
Spatial omics has emerged as a rapidly growing and fruitful field with hundreds of publications presenting novel methods for obtaining spatially resolved information for any omics data type on spatial...
10.