Ivan Protsyuk
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Explore the profile of Ivan Protsyuk including associated specialties, affiliations and a list of published articles.
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12
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1212
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Recent Articles
1.
Roy S, Mincu D, Loreaux E, Mottram A, Protsyuk I, Harris N, et al.
J Am Med Inform Assoc
. 2021 Jun;
28(9):1936-1946.
PMID: 34151965
Objective: Multitask learning (MTL) using electronic health records allows concurrent prediction of multiple endpoints. MTL has shown promise in improving model performance and training efficiency; however, it often suffers from...
2.
Tomasev N, Harris N, Baur S, Mottram A, Glorot X, Rae J, et al.
Nat Protoc
. 2021 May;
16(6):2765-2787.
PMID: 33953393
Early prediction of patient outcomes is important for targeting preventive care. This protocol describes a practical workflow for developing deep-learning risk models that can predict various clinical and operational outcomes...
3.
Nothias L, Petras D, Schmid R, Duhrkop K, Rainer J, Sarvepalli A, et al.
Nat Methods
. 2020 Aug;
17(9):905-908.
PMID: 32839597
Molecular networking has become a key method to visualize and annotate the chemical space in non-targeted mass spectrometry data. We present feature-based molecular networking (FBMN) as an analysis method in...
4.
Melnik A, Vazquez-Baeza Y, Aksenov A, Hyde E, McAvoy A, Wang M, et al.
mSystems
. 2019 Sep;
4(5).
PMID: 31551401
To visualize the personalized distributions of pathogens and chemical environments, including microbial metabolites, pharmaceuticals, and their metabolic products, within and between human lungs afflicted with cystic fibrosis (CF), we generated...
5.
Tomasev N, Glorot X, Rae J, Zielinski M, Askham H, Saraiva A, et al.
Nature
. 2019 Aug;
572(7767):116-119.
PMID: 31367026
The early prediction of deterioration could have an important role in supporting healthcare professionals, as an estimated 11% of deaths in hospital follow a failure to promptly recognize and treat...
6.
Nothias L, Nothias-Esposito M, da Silva R, Wang M, Protsyuk I, Zhang Z, et al.
J Nat Prod
. 2018 Mar;
81(4):758-767.
PMID: 29498278
It is a common problem in natural product therapeutic lead discovery programs that despite good bioassay results in the initial extract, the active compound(s) may not be isolated during subsequent...
7.
Kapono C, Morton J, Bouslimani A, Melnik A, Orlinsky K, Luzzatto Knaan T, et al.
Sci Rep
. 2018 Mar;
8(1):3669.
PMID: 29487294
One of the goals of forensic science is to identify individuals and their lifestyle by analyzing the trace signatures left behind in built environments. Here, microbiome and metabolomic methods were...
8.
Protsyuk I, Melnik A, Nothias L, Rappez L, Phapale P, Aksenov A, et al.
Nat Protoc
. 2017 Dec;
13(1):134-154.
PMID: 29266099
Our skin, our belongings, the world surrounding us, and the environment we live in are covered with molecular traces. Detecting and characterizing these molecular traces is necessary to understand the...
9.
Hartmann A, Petras D, Quinn R, Protsyuk I, Archer F, Ransome E, et al.
Proc Natl Acad Sci U S A
. 2017 Oct;
114(44):11685-11690.
PMID: 29078340
Untargeted metabolomics of environmental samples routinely detects thousands of small molecules, the vast majority of which cannot be identified. Meta-mass shift chemical (MeMSChem) profiling was developed to identify mass differences...
10.
Garg N, Wang M, Hyde E, da Silva R, Melnik A, Protsyuk I, et al.
Cell Host Microbe
. 2017 Oct;
22(5):705-716.e4.
PMID: 29056429
Our understanding of the spatial variation in the chemical and microbial makeup of an entire human organ remains limited, in part due to the size and heterogeneity of human organs...