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Theodora Hatziioannou

Explore the profile of Theodora Hatziioannou including associated specialties, affiliations and a list of published articles. Areas
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Citations 13271
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Recent Articles
11.
Witte L, Baharani V, Schmidt F, Wang Z, Cho A, Raspe R, et al.
Nat Commun . 2023 Jan; 14(1):302. PMID: 36653360
Waves of SARS-CoV-2 infection have resulted from the emergence of viral variants with neutralizing antibody resistance mutations. Simultaneously, repeated antigen exposure has generated affinity matured B cells, producing broadly neutralizing...
12.
Schaefer-Babajew D, Wang Z, Muecksch F, Cho A, Loewe M, Cipolla M, et al.
Nature . 2022 Dec; 613(7945):735-742. PMID: 36473496
Feedback inhibition of humoral immunity by antibodies was first documented in 1909. Subsequent studies showed that, depending on the context, antibodies can enhance or inhibit immune responses. However, little is...
13.
Wang Z, Zhou P, Muecksch F, Cho A, Ben Tanfous T, Canis M, et al.
J Exp Med . 2022 Sep; 219(12). PMID: 36149398
Individuals who receive a third mRNA vaccine dose show enhanced protection against severe COVID-19, but little is known about the impact of breakthrough infections on memory responses. Here, we examine...
14.
Yang L, Van Beek M, Wang Z, Muecksch F, Canis M, Hatziioannou T, et al.
bioRxiv . 2022 Sep; PMID: 36052368
The Omicron variant of SARS-CoV-2 evades neutralization by most serum antibodies elicited by two doses of mRNA vaccines, but a third dose of the same vaccine increases anti-Omicron neutralizing antibodies....
15.
Witte L, Baharani V, Schmidt F, Wang Z, Cho A, Raspe R, et al.
bioRxiv . 2022 Aug; PMID: 36032981
Consecutive waves of SARS-CoV-2 infection have been driven in part by the repeated emergence of variants with mutations that confer resistance to neutralizing antibodies Nevertheless, prolonged or repeated antigen exposure...
16.
Wang Z, Muecksch F, Muenn F, Cho A, Zong S, Raspe R, et al.
J Exp Med . 2022 Aug; 219(10). PMID: 36006380
The SARS-CoV-2 pandemic prompted a global vaccination effort and the development of numerous COVID-19 vaccines at an unprecedented scale and pace. As a result, current COVID-19 vaccination regimens comprise diverse...
17.
Schaefer-Babajew D, Wang Z, Muecksch F, Cho A, Raspe R, Johnson B, et al.
medRxiv . 2022 Aug; PMID: 35982682
Feedback inhibition of humoral immunity by antibodies was initially documented in guinea pigs by Theobald Smith in 1909, who showed that passive administration of excess anti-Diphtheria toxin inhibited immune responses....
18.
Gaebler C, DaSilva J, Bednarski E, Muecksch F, Schmidt F, Weisblum Y, et al.
Open Forum Infect Dis . 2022 Jul; 9(7):ofac227. PMID: 35818364
The emergence of severe acute respiratory syndrome coronavirus 2 variants that have greater transmissibility and resistance to neutralizing antibodies has increased the incidence of breakthrough infections. We show that breakthrough...
19.
Agudelo M, Muecksch F, Schaefer-Babajew D, Cho A, DaSilva J, Bednarski E, et al.
J Exp Med . 2022 Jul; 219(9). PMID: 35796685
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to be a global problem in part because of the emergence of variants of concern that evade neutralization by antibodies elicited by...
20.
Cho A, Muecksch F, Wang Z, Ben Tanfous T, DaSilva J, Raspe R, et al.
J Exp Med . 2022 Jul; 219(8). PMID: 35776090
The single-dose Ad.26.COV.2 (Janssen) vaccine elicits lower levels of neutralizing antibodies and shows more limited efficacy in protection against infection than either of the two available mRNA vaccines. In addition,...