Thamali Ayagama
Overview
Explore the profile of Thamali Ayagama including associated specialties, affiliations and a list of published articles.
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6
Citations
26
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0
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Recent Articles
1.
Ayagama T, Green P, Tan C, Monteiro C, Holdsworth D, Herring N
Exp Physiol
. 2025 Jan;
110(3):401-409.
PMID: 39861963
High cardiac sympathetic drive and release of the sympathetic cotransmitter neuropeptide Y (NPY) are significant features of congestive heart failure (CHF), in which resting venous NPY levels are known to...
2.
Akerman E, Read M, Bose S, Koschinski A, Capel R, Chao Y, et al.
Am J Physiol Heart Circ Physiol
. 2024 Aug;
327(4):H830-H846.
PMID: 39093001
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. Excessive stimulation of the inositol (1,4,5)-trisphosphate (IP) signaling pathway has been linked to AF through abnormal calcium handling. However, little...
3.
Bussmann B, Ayagama T, Liu K, Li D, Herring N
J Physiol
. 2024 Jun;
PMID: 38847435
William Bayliss and Ernest Starling are not only famous as pioneers in cardiovascular physiology, but also responsible for the discovery of the first hormone (from the Greek 'excite or arouse'),...
4.
Ayagama T, Charles P, Bose S, Boland B, Priestman D, Aston D, et al.
iScience
. 2024 Jun;
27(6):109609.
PMID: 38827406
Endolysosomes (EL) are known for their role in regulating both intracellular trafficking and proteostasis. EL facilitate the elimination of damaged membranes, protein aggregates, membranous organelles and play an important role...
5.
Bose S, Read M, Akerman E, Capel R, Ayagama T, Russell A, et al.
Front Pharmacol
. 2022 Sep;
13:951897.
PMID: 36105228
Atrial arrhythmias, such as atrial fibrillation (AF), are a major mortality risk and a leading cause of stroke. The IP signalling pathway has been proposed as an atrial-specific target for...
6.
Ayagama T, Bose S, Capel R, Priestman D, Berridge G, Fischer R, et al.
iScience
. 2021 Sep;
24(9):102949.
PMID: 34466782
The importance of lysosomes in cardiac physiology and pathology is well established, and evidence for roles in calcium signaling is emerging. We describe a label-free proteomics method suitable for small...
7.
Capel R, Bose S, Collins T, Rajasundaram S, Ayagama T, Zaccolo M, et al.
Am J Physiol Heart Circ Physiol
. 2020 Oct;
320(1):H95-H107.
PMID: 33064562
Inositol trisphosphate (IP) is a Ca-mobilizing second messenger shown to modulate atrial muscle contraction and is thought to contribute to atrial fibrillation. Cellular pathways underlying IP actions in cardiac tissue...