Tetsuya Yoshino
Overview
Explore the profile of Tetsuya Yoshino including associated specialties, affiliations and a list of published articles.
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5
Citations
19
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0
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Recent Articles
1.
Yoshino T, Ishikawa T, Ishihara T, Takeuchi Y, Yoshikawa H, Yoshida H, et al.
Biol Pharm Bull
. 2011 Aug;
34(8):1273-8.
PMID: 21804217
Therapeutic monoclonal antibodies (MAbs) with high specificity and fewer adverse effects are becoming widely used for the treatment of various diseases. MAbs need to be stored and administered at high...
2.
Nishiyama U, Yoshino T, Ozai M, Yoshioka R, Fujisawa M, Ogasawara Y, et al.
Leuk Res
. 2006 Apr;
30(12):1541-6.
PMID: 16603240
Activating mutations of Fms-like tyrosine kinase 3 (Flt3) are the most common genetic abnormalities found in acute myeloid leukemia (AML) and represent potential therapeutic targets. The novel Flt3 inhibitor KRN383...
3.
Furuta T, Sakai T, Senga T, Osawa T, Kubo K, Shimizu T, et al.
J Med Chem
. 2006 Mar;
49(7):2186-92.
PMID: 16570914
We report the structure-activity relationship of quinoline and quinazoline derivatives, which include urea, thiourea, urethane, and acylthiourea groups, as inhibitors of the platelet-derived growth factor (PDGF) receptor autophosphorylation. Our previous...
4.
Shimizu T, Fujiwara Y, Osawa T, Sakai T, Kubo K, Kubo K, et al.
Bioorg Med Chem Lett
. 2004 Mar;
14(4):875-9.
PMID: 15012985
(6,7-Disubstituted-quinolin-4-yloxy-phenyl)(4-substituted-phenyl)amine derivatives were synthesized and evaluated by a cellular autophosphorylation assay for FGF-R2 in the human scirrhous gastric carcinoma cell line, OCUM-2MD3. We also performed metabolic stability studies showing that...
5.
Yano K, Yoshino T, Shionoya M, Sawata S, Ikebukuro K, Karube I
Biosens Bioelectron
. 2003 Jul;
18(10):1201-7.
PMID: 12835037
A novel phage library has been prepared using the Escherichia coli genome digested with three restriction enzymes. The resulting DNA fragments were ligated to the expression vector pCANTAB5 to obtain...