Shinya Y Sawata
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Explore the profile of Shinya Y Sawata including associated specialties, affiliations and a list of published articles.
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10
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65
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Recent Articles
1.
Kato Y, Sawata S, Inoue A
J Biochem
. 2009 Sep;
147(1):63-71.
PMID: 19762345
MicroRNAs (miRNAs) are non-coding small RNAs that have been found in various kinds of eukaryotes and viruses. Recently, adenovirus non-coding RNAs, VA RNAs, have been reported to generate miRNAs. Here,...
2.
Wada A, Sawata S, Ito Y
Biotechnol Bioeng
. 2008 Jul;
101(5):1102-7.
PMID: 18613123
A new ribosome display system was applied for the in vitro selection of a metal-binding motif from an artificial peptide library. The display system consisted of an mRNA-associating protein, a...
3.
Inoue A, Sawata S, Taira K, Wadhwa R
Proc Natl Acad Sci U S A
. 2007 May;
104(21):8983-8.
PMID: 17483488
We have developed a loss-of-function screening system on the basis of intracellular expression of single domain antibodies. We demonstrate its use in identification of potential targets of metastasis of human...
4.
Miyagishi M, Matsumoto S, Akashi H, Kawasaki H, Fukao T, Fukuda Y, et al.
Nucleic Acids Symp Ser (Oxf)
. 2006 Dec;
(49):91-2.
PMID: 17150648
Mechanism of action of hammerhead ribozymes has been investigated and their intracellular activities have been improved. Based on the improved ribozymes and more recently discovered natural RNAi, we have created...
5.
Inoue A, Sawata S, Taira K
J Drug Target
. 2006 Oct;
14(7):448-55.
PMID: 17062391
Double stranded short interfering RNAs (siRNAs) mediate gene silencing in a sequence specific manner. By virtue of their specific gene silencing activity and owing to the recent discoveries on their...
6.
Sawata S, Suyama E, Taira K
Protein Eng Des Sel
. 2004 Aug;
17(6):501-8.
PMID: 15292519
Ribosome display systems are very effective and powerful tools for in vitro screening of transcribed mRNAs that encode proteins (or peptides) with specific (known or unknown) functions. We have modified...
7.
Sawata S, Taira K
Protein Eng
. 2004 Feb;
16(12):1115-24.
PMID: 14983094
The ribosome display system is a very effective and powerful tool for in vitro screening of transcribed mRNAs that encode proteins (or peptides) with specific (known or unknown) functions. The...
8.
Fujita S, Sawata S, Taira K
Tanpakushitsu Kakusan Koso
. 2003 Aug;
48(11 Suppl):1464-73.
PMID: 12931601
No abstract available.
9.
Yano K, Yoshino T, Shionoya M, Sawata S, Ikebukuro K, Karube I
Biosens Bioelectron
. 2003 Jul;
18(10):1201-7.
PMID: 12835037
A novel phage library has been prepared using the Escherichia coli genome digested with three restriction enzymes. The resulting DNA fragments were ligated to the expression vector pCANTAB5 to obtain...
10.
Fujita S, Sawata S, Yamamoto-Fujita R, Endo Y, Kise H, Iwakura M, et al.
J Med Chem
. 2002 Apr;
45(8):1598-606.
PMID: 11931614
We recently isolated an aptamer that binds to the Tat protein of HIV-1 with extremely high affinity and specificity (Yamamoto, R.; et al. Genes Cells 2000, 5, 371.). In the...