Tetsuya Sakairi
Overview
Explore the profile of Tetsuya Sakairi including associated specialties, affiliations and a list of published articles.
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18
Citations
175
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Recent Articles
1.
Suzuki S, Mizukawa M, Kashimura A, Nishina H, Sakairi T, Nishikawa S
J Toxicol Pathol
. 2024 Oct;
37(4):189-195.
PMID: 39359897
B-cell lymphoma is generally observed in the spleen, mesenteric lymph nodes, and Peyer's patches in aged mice and rarely appears in other organs. Herein, we report a case of spontaneous...
2.
Kashimura A, Nishikawa S, Ozawa Y, Hibino Y, Tateoka T, Mizukawa M, et al.
J Toxicol Pathol
. 2024 Apr;
37(2):69-82.
PMID: 38584972
In drug development, assessment of non-clinical peripheral neurotoxicity is important to ensure human safety. Clarifying the pathological features and mechanisms of toxicity enables the management of safety risks in humans...
3.
Nishina H, Sakairi T, Kashimura A, Sato H, Mizukawa M, Ozawa Y, et al.
J Toxicol Pathol
. 2021 Oct;
34(4):367-371.
PMID: 34629736
Antisense oligonucleotide (ASO) therapies have been identified as a new treatment modality for intractable diseases. In kidneys treated with ASOs, vacuoles, in addition to basophilic granules, are often observed in...
4.
Mizukawa M, Sato H, Nishikawa S, Kashimura A, Nishina H, Sakairi T
J Toxicol Pathol
. 2021 Feb;
34(1):123-125.
PMID: 33627954
This paper describes the spontaneous ovarian choriocarcinoma observed in a young female Crl:CD1 (ICR) mouse. The mouse was sacrificed at 8 weeks of age after oral administration of a compound...
5.
Nishina H, Kashimura A, Sakairi T, Nishikawa S, Mizukawa M, Sato H
J Toxicol Pathol
. 2020 Nov;
33(4):303-307.
PMID: 33239849
Hyaline glomerulopathy is a type of glomerular lesion that occurs in aging mice. Spontaneous hyaline glomerulopathy is rare in young mice. Here, we report spontaneous hyaline glomerulopathy in a young...
6.
Miyazaki H, Ikeda Y, Sakurai O, Miyake T, Tsubota R, Okabe J, et al.
Bioorg Med Chem Lett
. 2018 May;
28(11):2055-2060.
PMID: 29724589
The calcium-sensing receptor (CaSR) plays an important role in sensing extracellular calcium ions and regulating parathyroid hormone secretion by parathyroid gland cells, and the receptor is a suitable target for...
7.
Sato H, Terasaki N, Sakairi T, Tanaka M, Takahashi K
Exp Toxicol Pathol
. 2015 Jan;
67(2):205-10.
PMID: 25579645
Pulmonary thrombosis is a life-threatening disorder caused by various risk factors. We previously reported that phenylhydrazine (PHZ) induces acute thrombosis in the rat lung, with regional stasis in the alveolar...
8.
Sato H, Sakairi T, Fujimura H, Sugimoto J, Kume E, Kitamura K, et al.
Exp Toxicol Pathol
. 2012 Mar;
65(4):457-62.
PMID: 22402172
Abnormality in hematological condition including hemolytic disorders has been suggested one of the risk factor of pulmonary thrombosis. We previously reported that phenylhydrazine (PHZ) could induce acute thrombosis in the...
9.
Kawai K, Sakairi T, Tanaka M, Shinozuka J, Ide M, Sato H, et al.
J Toxicol Pathol
. 2012 Feb;
23(1):59-62.
PMID: 22319226
A hepatic nodule was noted in a C57BL/6J mouse with diet-induced obesity at 53 weeks of age. Macroscopically, a protruding yellowish white nodule was observed on the visceral surface of...
10.
Nishikawa S, Sugimoto J, Okada M, Sakairi T, Takagi S
Toxicol Pathol
. 2011 Nov;
40(1):71-82.
PMID: 22105644
We previously demonstrated that high-fat diet (HFD)-induced hepatic lipid accumulation is more severe in BALB/c mice than in C57BL/6J (B6) mice. To understand the changes in liver metabolism, we studied...