Tet Woo Lee
Overview
Explore the profile of Tet Woo Lee including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
178
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0
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Recent Articles
1.
Lee T, Singleton D, Harms J, Lu M, McManaway S, Lai A, et al.
Mol Oncol
. 2024 Mar;
18(8):1885-1903.
PMID: 38426642
Tumour hypoxia promotes poor patient outcomes, with particularly strong evidence for head and neck squamous cell carcinoma (HNSCC). To effectively target hypoxia, therapies require selection biomarkers and preclinical models that...
2.
Jose J, Law R, Leung E, Wai D, Akhlaghi H, Chandrashekaran I, et al.
Eur J Med Chem
. 2023 Sep;
261:115786.
PMID: 37716187
Perforin is a pore-forming protein whose normal function enables cytotoxic T and natural killer (NK) cells to kill virus-infected and transformed cells. Conversely, unwanted perforin activity can also result in...
3.
Lee T, Hunter F, Tsai P, Print C, Wilson W, Jamieson S
Cancer Gene Ther
. 2023 Sep;
30(12):1610-1623.
PMID: 37684549
Transplantable in vivo CRISPR/Cas9 knockout screens, in which cells are edited in vitro and inoculated into mice to form tumours, allow evaluation of gene function in a cancer model that...
4.
Jamieson S, Tsai P, Kondratyev M, Budhani P, Liu A, Senzer N, et al.
JCI Insight
. 2023 Feb;
8(4).
PMID: 36810255
No abstract available.
5.
Lee T, Lai A, Harms J, Singleton D, Dickson B, Macann A, et al.
Cancers (Basel)
. 2020 Dec;
12(12).
PMID: 33322840
Patient survival from head and neck squamous cell carcinoma (HNSCC), the seventh most common cause of cancer, has not markedly improved in recent years despite the approval of targeted therapies...
6.
Lee T, Wong W, Dickson B, Lipert B, Cheng G, Hunter F, et al.
Int J Radiat Biol
. 2019 Sep;
95(12):1597-1612.
PMID: 31490091
Poly(ADP-ribose)polymerase-1 (PARP1) and DNA-dependent protein kinase (DNA-PK) play key roles in the repair of radiation-induced DNA double strand breaks, but it is unclear which is the preferred therapeutic target in...
7.
Jamieson S, Tsai P, Kondratyev M, Budhani P, Liu A, Senzer N, et al.
JCI Insight
. 2018 Aug;
3(16).
PMID: 30135316
Evofosfamide (TH-302) is a clinical-stage hypoxia-activated prodrug of a DNA-crosslinking nitrogen mustard that has potential utility for human papillomavirus (HPV) negative head and neck squamous cell carcinoma (HNSCC), in which...
8.
Lee T, Tsang V, Loef E, Birch N
Semin Cell Dev Biol
. 2016 Sep;
62:152-159.
PMID: 27639894
It is 27 years since neuroserpin was first discovered in the nervous system and identified as a member of the serpin superfamily. Since that time potential roles for this serine...
9.
Lee T, Tsang V, Birch N
Front Cell Neurosci
. 2015 Nov;
9:396.
PMID: 26528129
Although its roles in the vascular space are most well-known, tissue plasminogen activator (tPA) is widely expressed in the developing and adult nervous system, where its activity is believed to...
10.
Robinson S, Lee T, Christie D, Birch N
Front Cell Neurosci
. 2015 Oct;
9:404.
PMID: 26500501
NMDA receptors (NMDARs) play a critical role in neurotransmission, acting as essential mediators of many forms of synaptic plasticity, and also modulating aspects of development, synaptic transmission and cell death....