Terje Espevik
Overview
Explore the profile of Terje Espevik including associated specialties, affiliations and a list of published articles.
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Articles
133
Citations
7837
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Recent Articles
1.
Zhang B, Orning P, Lehman J, Dinis A, Torres-Ulloa L, Elling R, et al.
Proc Natl Acad Sci U S A
. 2025 Feb;
122(7):e2420802122.
PMID: 39946533
Multiple cell death and inflammatory signaling pathways converge on two critical factors: receptor-interacting serine/threonine kinase 1 (RIPK1) and caspase-8. Careful regulation of these molecules is critical to control apoptosis, pyroptosis,...
2.
Zhang B, Orning P, Lehman J, Dinis A, Torres-Ulloa L, Elling R, et al.
bioRxiv
. 2024 Dec;
PMID: 39651143
Significance: Caspase-8 and the kinase RIPK1 are at focal points of several inflammation and cell death pathways. Thus, a careful regulation of their actions is needed. Our work identifies the...
3.
Fagerang B, Cyranka L, Schjalm C, McAdam K, Larsen C, Heinzelbecker J, et al.
Front Immunol
. 2024 Jun;
15:1422370.
PMID: 38938578
Introduction: Hematopoietic stem cell transplantation (HSCT) is associated with immune complications and endothelial dysfunction due to intricate donor-recipient interactions, conditioning regimens, and inflammatory responses. Methods: This study investigated the role...
4.
Olsen M, Kong X, Louwe M, Lauritzen K, Schanke Y, Kaasboll O, et al.
Front Immunol
. 2024 Apr;
15:1383505.
PMID: 38686379
Acute myocardial infarction (MI) results in tissue damage to affected areas of the myocardium. The initial inflammatory response is the most damaging for residual cardiac function, while at later stages...
5.
Nilsen K, Zhang B, Skjesol A, Ryan L, Vagle H, Boe M, et al.
Life Sci Alliance
. 2023 Oct;
6(12).
PMID: 37788908
Inflammation plays a crucial role in the development and progression of many diseases, and is often caused by dysregulation of signalling from pattern recognition receptors, such as TLRs. Inhibition of...
6.
Lentini G, Fama A, De Gaetano G, Coppolino F, Mahjoub A, Ryan L, et al.
Cell Rep Med
. 2023 Jun;
4(7):101098.
PMID: 37390829
During differentiation, neutrophils undergo a spontaneous pro-inflammatory program that is hypothesized here to be under caspase-8 control. In mice, intraperitoneal administration of the caspase-8 inhibitor z-IETD-fmk is sufficient to unleash...
7.
Bjerkhaug A, Granslo H, Cavanagh J, Hoiland I, Ludviksen J, Lau C, et al.
Pediatr Res
. 2023 Feb;
94(2):512-519.
PMID: 36725909
Background: Escherichia coli and Group B streptococci (GBS) are the main causes of neonatal early-onset sepsis (EOS). Despite antibiotic therapy, EOS is associated with high morbidity and mortality. Dual inhibition...
8.
Pinto S, Subbannayya Y, Kim H, Hagen L, Gorna M, Nieminen A, et al.
iScience
. 2023 Jan;
26(1):105895.
PMID: 36590899
COVID-19 pandemic continues to remain a global health concern owing to the emergence of newer variants. Several multi-Omics studies have produced extensive evidence on host-pathogen interactions and potential therapeutic targets....
9.
Nilsen K, Skjesol A, Frengen Kojen J, Espevik T, Stenvik J, Yurchenko M
Biomedicines
. 2022 Jul;
10(7).
PMID: 35884781
Toll-like receptor 8 (TLR8) recognizes single-stranded RNA of viral and bacterial origin as well as mediates the secretion of pro-inflammatory cytokines and type I interferons by human monocytes and macrophages....
10.
Johnson C, Quach H, Lau C, Ekholt K, Espevik T, Woodruff T, et al.
J Immunol
. 2022 Jun;
208(12):2771-2778.
PMID: 35675954
Thrombin plays a central role in thromboinflammatory responses, but its activity is blocked in the common ex vivo human whole blood models, making an ex vivo study of thrombin effects...