Teresa R Kee
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Explore the profile of Teresa R Kee including associated specialties, affiliations and a list of published articles.
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10
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52
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Recent Articles
1.
Sridharan P, Koh Y, Miller E, Hu D, Chakraborty S, Tripathi S, et al.
Cell Rep Med
. 2024 Sep;
5(9):101715.
PMID: 39241772
Progression of acute traumatic brain injury (TBI) into chronic neurodegeneration is a major health problem with no protective treatments. Here, we report that acutely elevated mitochondrial fission after TBI in...
2.
Karunarathne K, Kee T, Jeon H, Cazzaro S, Gamage Y, Pan J, et al.
Biomolecules
. 2024 Jun;
14(6).
PMID: 38927020
Deposition of extracellular Amyloid Beta (Aβ) and intracellular tau fibrils in post-mortem brains remains the only way to conclusively confirm cases of Alzheimer's Disease (AD). Substantial evidence, though, implicates small...
3.
Kee T, Khan S, Neidhart M, Masters B, Zhao V, Kim Y, et al.
Exp Mol Med
. 2024 Jan;
56(1):129-141.
PMID: 38212557
Arrestins are multifunctional proteins that regulate G-protein-coupled receptor (GPCR) desensitization, signaling, and internalization. The arrestin family consists of four subtypes: visual arrestin1, β-arrestin1, β-arrestin2, and visual arrestin-4. Recent studies have...
4.
Liu T, Wetzel L, Zhu Z, Kumaraguru P, Gorthi V, Yan Y, et al.
Cells
. 2023 Dec;
12(24).
PMID: 38132101
Coiled-coil-helix-coiled-coil-helix domain-containing 10 (CHCHD10) is a nuclear-encoded mitochondrial protein which is primarily mutated in the spectrum of familial and sporadic amyotrophic lateral sclerosis (ALS)-frontotemporal dementia (FTD). Endogenous CHCHD10 levels decline...
5.
Cazzaro S, Woo J, Wang X, Liu T, Rego S, Kee T, et al.
Proc Natl Acad Sci U S A
. 2023 Jul;
120(30):e2217128120.
PMID: 37463212
Oxidative damage in the brain is one of the earliest drivers of pathology in Alzheimer's disease (AD) and related dementias, both preceding and exacerbating clinical symptoms. In response to oxidative...
6.
Woo J, Castano M, Kee T, Lee J, Koziol-White C, An S, et al.
Am J Respir Cell Mol Biol
. 2023 Jan;
68(4):417-429.
PMID: 36662576
TAS2Rs (bitter taste receptors) are GPCRs (G protein-coupled receptors) expressed on human airway smooth muscle (HASM) cells; when activated by receptor agonists they evoke marked airway relaxation. In both taste...
7.
Cazzaro S, Fang C, Khan H, Witas R, Kee T, Woo J, et al.
Front Aging Neurosci
. 2022 Sep;
14:933979.
PMID: 36092812
Increasing evidence indicates that the accumulation misfolded proteins in Alzheimer's disease (AD) arises from clearance defects in the autophagy-lysosome pathway. Misfolded proteins such as Aβ and tau are secreted in...
8.
Kee T, Wehinger J, Espinoza Gonzalez P, Nguyen E, McGill Percy K, Khan S, et al.
Hum Mol Genet
. 2022 Jul;
31(23):3987-4005.
PMID: 35786718
Coiled-coil-helix-coiled-coil-helix domain containing 2 (CHCHD2) is a mitochondrial protein that plays important roles in cristae structure, oxidative phosphorylation and apoptosis. Multiple mutations in CHCHD2 have been associated with Lewy body...
9.
Woo J, Yan Y, Kee T, Cazzaro S, McGill Percy K, Wang X, et al.
Life Sci Alliance
. 2021 Dec;
5(3).
PMID: 34862271
G protein-coupled receptors (GPCRs) have been shown to play integral roles in Alzheimer's disease pathogenesis. However, it is unclear how diverse GPCRs similarly affect Aβ and tau pathogenesis. GPCRs share...
10.
Kee T, Espinoza Gonzalez P, Wehinger J, Bukhari M, Ermekbaeva A, Sista A, et al.
Front Aging Neurosci
. 2021 May;
13:660843.
PMID: 33967741
Rare mutations in the mitochondrial protein coiled-coil-helix-coiled-coil-helix domain containing 2 (CHCHD2) are associated with Parkinson's disease (PD) and other Lewy body disorders. CHCHD2 is a bi-organellar mediator of oxidative phosphorylation,...