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Terence F McGuire

Explore the profile of Terence F McGuire including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Cuyler J, Murthy P, Spada N, McGuire T, Lotze M, Xie X
Drug Discov Today . 2021 Sep; 27(1):362-370. PMID: 34592447
Pancreatic ductal adenocarcinoma (PDAC) is characterized by heightened autophagy and systemic immune dysfunction. Modest improvements in clinical outcomes have been demonstrated in completed clinical trials targeting autophagy with combination hydroxychloroquine...
2.
Elster J, McGuire T, Lu J, Prochownik E
PLoS One . 2013 Oct; 8(10):e77675. PMID: 24130897
The development of an independent blood supply by a tumor is essential for maintaining growth beyond a certain limited size and for providing a portal for metastatic dissemination. Host-derived endothelial...
3.
McGuire T, Sajithlal G, Lu J, Nicholls R, Prochownik E
PLoS One . 2012 May; 7(5):e37138. PMID: 22623986
The growth of a malignant tumor beyond a certain, limited size requires that it first develop an independent blood supply. In addition to providing metabolic support, this neovasculature also allows...
4.
Sajithlal G, McGuire T, Lu J, Beer-Stolz D, Prochownik E
Int J Cancer . 2010 Feb; 127(10):2268-78. PMID: 20162569
Tumor-associated endothelial cells (TAECs) harboring various genomic abnormalities have been described in human cancers although their origins remain obscure. We generated 4 human cancer cell lines tagged with multiple markers,...
5.
Hershberger P, McGuire T, Yu W, Zuhowski E, Schellens J, Egorin M, et al.
Mol Cancer Ther . 2002 Dec; 1(10):821-9. PMID: 12492115
1,25-Dihydroxyvitamin D3 (1,25D3) exhibits potent antitumor activity in the murine squamous cell carcinoma (SCC) SCCVII/SF, and the combination of 1,25D3 with cisplatin (1,25D3/cisplatin) demonstrates even greater activity. Because these agents...
6.
Johnson C, Hershberger P, Bernardi R, McGuire T, Trump D
Urology . 2002 Sep; 60(3 Suppl 1):123-30; discussion 130-1. PMID: 12231068
Epidemiologic data suggest that low exposure to vitamin D or 1alpha,25-dihydroxycholecalciferol (calcitriol) increases the risk of prostate cancer. Calcitriol, a central factor in bone and mineral metabolism, is also a...