Gangadharan B Sajithlal
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Explore the profile of Gangadharan B Sajithlal including associated specialties, affiliations and a list of published articles.
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79
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Recent Articles
1.
Cruickshanks N, Hamed H, Booth L, Tavallai S, Syed J, Sajithlal G, et al.
Cancer Biol Ther
. 2013 Sep;
14(10):982-96.
PMID: 24025251
The present studies focused on defining the mechanisms by which anoikis-resistant (AR) mammary carcinoma cells can be reverted to a therapy-sensitive phenotype. AR mammary carcinoma cells had reduced expression of...
2.
Sajithlal G, Hamed H, Cruickshanks N, Booth L, Tavallai S, Syed J, et al.
Mol Pharmacol
. 2013 Jul;
84(4):562-71.
PMID: 23877009
The present studies were undertaken to determine whether the multikinase inhibitors sorafenib/regorafenib cooperated with clinically relevant , phosphatidyl inositol 3 kinase (PI3K)-thymoma viral proto-oncogene (AKT) inhibitors to kill tumor cells....
3.
McGuire T, Sajithlal G, Lu J, Nicholls R, Prochownik E
PLoS One
. 2012 May;
7(5):e37138.
PMID: 22623986
The growth of a malignant tumor beyond a certain, limited size requires that it first develop an independent blood supply. In addition to providing metabolic support, this neovasculature also allows...
4.
Sajithlal G, Rothermund K, Zhang F, Dabbs D, Latimer J, Grant S, et al.
Stem Cells
. 2010 May;
28(6):1008-18.
PMID: 20506227
Cancer stem cells (CSCs) are thought to be resistant to standard chemotherapeutic drugs and the inimical conditions of the tumor microenvironment. Obtaining CSCs in sufficient quantities and maintaining their undifferentiated...
5.
Sajithlal G, McGuire T, Lu J, Beer-Stolz D, Prochownik E
Int J Cancer
. 2010 Feb;
127(10):2268-78.
PMID: 20162569
Tumor-associated endothelial cells (TAECs) harboring various genomic abnormalities have been described in human cancers although their origins remain obscure. We generated 4 human cancer cell lines tagged with multiple markers,...