Teodoro Vargas
Overview
Explore the profile of Teodoro Vargas including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
366
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0
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Recent Articles
1.
Mouhid L, Gomez de Cedron M, Vargas T, Garcia-Carrascosa E, Herranz N, Garcia-Risco M, et al.
BMC Complement Altern Med
. 2018 Sep;
18(1):254.
PMID: 30223811
Background: Pancreatic cancer is one of the most aggressive and mortal cancers. Although several drugs have been proposed for its treatment, it remains resistant and new alternatives are needed. In...
2.
Gomez de Cedron M, Vargas T, Madrona A, Jimenez A, Perez-Perez M, Quintela J, et al.
J Pharmacol Exp Ther
. 2018 Jun;
366(2):377-389.
PMID: 29871992
New series of polyphenols with a hydrophilic galloyl-based head and a hydrophobic -acyl tail, linked through a serinol moiety, have been synthesized and tested against colon cancer cell growth. Our...
3.
Fernandez L, Sanchez-Martinez R, Vargas T, Herranz J, Martin-Hernandez R, Mendiola M, et al.
Sci Rep
. 2018 Jun;
8(1):8485.
PMID: 29855486
Glycosyltransferase enzyme GCNT3, has been proposed as a biomarker for prognosis in colorectal cancer (CRC). Our study goes in depth into the molecular basis of GCNT3 role in tumorigenesis and...
4.
Fernandez L, Ramos-Ruiz R, Herranz J, Martin-Hernandez R, Vargas T, Mendiola M, et al.
Oncotarget
. 2018 Feb;
9(5):5919-5930.
PMID: 29464044
Metabolic alterations encountered in tumors are well recognized and considered as a hallmark of cancer. In addition to Warburg Effect, epidemiological and experimental studies support the crucial role of lipid...
5.
Cruz-Gil S, Sanchez-Martinez R, Gomez de Cedron M, Martin-Hernandez R, Vargas T, Molina S, et al.
J Lipid Res
. 2017 Oct;
59(1):14-24.
PMID: 29074607
An abnormal acyl-CoA synthetase/stearoyl-CoA desaturase (/) lipid network fuels colon cancer progression, endowing cells with invasive and migratory properties. Therapies against this metabolic network may be useful to improve clinical...
6.
Vargas T, Moreno-Rubio J, Herranz J, Cejas P, Molina S, Mendiola M, et al.
PLoS One
. 2016 Dec;
11(12):e0168423.
PMID: 27992526
Strong evidence suggests that lipid metabolism (LM) has an essential role in tumor growth to support special energetic and structural requirements of tumor cells. Recently, overexpression of LM-related genes, apolipoproteins...
7.
Sanchez-Martinez R, Cruz-Gil S, Gomez de Cedron M, Alvarez-Fernandez M, Vargas T, Molina S, et al.
Oncotarget
. 2015 Oct;
6(36):38719-36.
PMID: 26451612
The alterations in carbohydrate metabolism that fuel tumor growth have been extensively studied. However, other metabolic pathways involved in malignant progression, demand further understanding. Here we describe a metabolic acyl-CoA...
8.
Ramirez de Molina A, Vargas T, Molina S, Sanchez J, Martinez-Romero J, Gonzalez-Vallinas M, et al.
J Pharmacol Exp Ther
. 2015 Mar;
353(2):433-44.
PMID: 25758919
Ellagic acid (EA) and some derivatives have been reported to inhibit cancer cell proliferation, induce cell cycle arrest, and modulate some important cellular processes related to cancer. This study aimed...
9.
Vargas T, Moreno-Rubio J, Herranz J, Cejas P, Molina S, Gonzalez-Vallinas M, et al.
Oncotarget
. 2015 Mar;
6(9):7348-63.
PMID: 25749516
Lipid metabolism plays an essential role in carcinogenesis due to the requirements of tumoral cells to sustain increased structural, energetic and biosynthetic precursor demands for cell proliferation. We investigated the...
10.
Gonzalez-Vallinas M, Vargas T, Moreno-Rubio J, Molina S, Herranz J, Cejas P, et al.
Eur J Cancer
. 2014 Dec;
51(1):1-8.
PMID: 25466507
Altered glycosylation is considered a universal cancer hallmark. Mucin-type core 2 1,6-N-acetylglucosaminyltransferase enzyme (C2GnT-M), encoded by the GCNT3 gene, has been reported to be altered in tumours and to possess...