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Teddy Grandjean

Explore the profile of Teddy Grandjean including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 1081
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Recent Articles
1.
Muharram G, Thepaut M, Lobert P, Grandjean T, Boulard O, Delacre M, et al.
Gut Microbes . 2023 Sep; 15(2):2249960. PMID: 37655966
Over 90% of epidemic non-bacterial gastroenteritis are caused by human noroviruses (NoVs), which persist in a substantial subset of people allowing their spread worldwide. This has led to a significant...
2.
Louis M, Tahrioui A, Tremlett C, Clamens T, Leprince J, Lefranc B, et al.
Biofilm . 2023 May; 5:100131. PMID: 37252226
Biofilms are highly tolerant to antimicrobials and host immune defense, enabling pathogens to thrive in hostile environments. The diversity of microbial biofilm infections requires alternative and complex treatment strategies. In...
3.
Le Guern R, Grandjean T, Stabler S, Bauduin M, Gosset P, Kipnis E, et al.
Nat Commun . 2023 Jan; 14(1):78. PMID: 36604442
Carbapenemase-producing Enterobacterales (CPE) are spreading rapidly in hospital settings. Asymptomatic CPE gut colonisation may be associated with dysbiosis and gut-lung axis alterations, which could impact lung infection outcomes. In this...
4.
Secher T, Couturier A, Huot L, Bouscayrol H, Grandjean T, Boulard O, et al.
J Crohns Colitis . 2022 Aug; 17(1):111-122. PMID: 35917251
Background And Aims: NOD2 has emerged as a critical player in the induction of both Th1 and Th2 responses for potentiation and polarisation of antigen-dependent immunity. Loss-of-function mutations in the...
5.
Le Goff M, Vastel M, Lebrun R, Mansuelle P, Diarra A, Grandjean T, et al.
Front Cell Infect Microbiol . 2022 Jul; 12:859181. PMID: 35782124
Bacteria of the genus are environmental germs, with an unknown reservoir. It can become opportunistic pathogens in immunocompromised patients, causing bacteremia, meningitis, pneumonia, or peritonitis. In recent years, has emerged...
6.
Louis M, Clamens T, Tahrioui A, Desriac F, Rodrigues S, Rosay T, et al.
Adv Sci (Weinh) . 2022 Jan; 9(7):e2103262. PMID: 35032112
Pseudomonas aeruginosa biofilms cause chronic, antibiotic tolerant infections in wounds and lungs. Numerous recent studies demonstrate that bacteria can detect human communication compounds through specific sensor/receptor tools that modulate bacterial...
7.
Loquet A, Le Guern R, Grandjean T, Duployez C, Bauduin M, Kipnis E, et al.
J Mol Diagn . 2020 Dec; 23(2):234-241. PMID: 33259953
Bacterial vaginosis (BV) diagnosis in pregnancy is based on the Nugent score, which consists of semiquantitation of bacterial morphotypes. Limited data exist concerning molecular-based diagnosis in asymptomatic pregnant women. Using...
8.
Dessein R, Bauduin M, Grandjean T, Le Guern R, Figeac M, Beury D, et al.
Crit Care . 2020 Oct; 24(1):611. PMID: 33076936
Background: Gut dysbiosis due to the adverse effects of antibiotics affects outcomes of lung infection. Previous murine models relied on significant depletion of both gut and lung microbiota, rendering the...
9.
Le Guern R, Grandjean T, Bauduin M, Figeac M, Millot G, Loquet A, et al.
Antimicrob Agents Chemother . 2019 Apr; 63(6). PMID: 30962336
While antibiotic use is a risk factor of carbapenemase-producing (CPE) acquisition, the importance of timing of antibiotic administration relative to CPE exposure remains unclear. In a murine model of gut...
10.
Le Guern R, Grandjean T, Faure K, Bauduin M, Kipnis E, Dessein R
Microbiol Resour Announc . 2018 Dec; 7(8). PMID: 30533912
Carbapenemase-producing Klebsiella pneumoniae represents an emerging public health issue. Here, we present the draft whole-genome sequences of K. pneumoniae clinical strains KPL0.1 (OXA-48 carbapenemase) and KPL0.2 (NDM-1 carbapenemase). These genome...