Ted Sharpe
Overview
Explore the profile of Ted Sharpe including associated specialties, affiliations and a list of published articles.
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23
Citations
8519
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Recent Articles
11.
Bradnam K, Fass J, Alexandrov A, Baranay P, Bechner M, Birol I, et al.
Gigascience
. 2013 Jul;
2(1):10.
PMID: 23870653
Background: The process of generating raw genome sequence data continues to become cheaper, faster, and more accurate. However, assembly of such data into high-quality, finished genome sequences remains challenging. Many...
12.
Amemiya C, Alfoldi J, Lee A, Fan S, Philippe H, MacCallum I, et al.
Nature
. 2013 Apr;
496(7445):311-6.
PMID: 23598338
The discovery of a living coelacanth specimen in 1938 was remarkable, as this lineage of lobe-finned fish was thought to have become extinct 70 million years ago. The modern coelacanth...
13.
Berglund J, Nevalainen E, Molin A, Perloski M, Andre C, Zody M, et al.
Genome Biol
. 2012 Aug;
13(8):R73.
PMID: 22916802
Background: Copy number variants (CNVs) account for substantial variation between genomes and are a major source of normal and pathogenic phenotypic differences. The dog is an ideal model to investigate...
14.
Ribeiro F, Przybylski D, Yin S, Sharpe T, Gnerre S, Abouelleil A, et al.
Genome Res
. 2012 Jul;
22(11):2270-7.
PMID: 22829535
Exceptionally accurate genome reference sequences have proven to be of great value to microbial researchers. Thus, to date, about 1800 bacterial genome assemblies have been "finished" at great expense with...
15.
Earl D, Bradnam K, St John J, Darling A, Lin D, Fass J, et al.
Genome Res
. 2011 Sep;
21(12):2224-41.
PMID: 21926179
Low-cost short read sequencing technology has revolutionized genomics, though it is only just becoming practical for the high-quality de novo assembly of a novel large genome. We describe the Assemblathon...
16.
Gnerre S, MacCallum I, Przybylski D, Ribeiro F, Burton J, Walker B, et al.
Proc Natl Acad Sci U S A
. 2010 Dec;
108(4):1513-8.
PMID: 21187386
Massively parallel DNA sequencing technologies are revolutionizing genomics by making it possible to generate billions of relatively short (~100-base) sequence reads at very low cost. Whereas such data can be...
17.
Barretina J, Taylor B, Banerji S, Ramos A, Lagos-Quintana M, DeCarolis P, et al.
Nat Genet
. 2010 Jul;
42(8):715-21.
PMID: 20601955
Soft-tissue sarcomas, which result in approximately 10,700 diagnoses and 3,800 deaths per year in the United States, show remarkable histologic diversity, with more than 50 recognized subtypes. However, knowledge of...
18.
Rubin C, Zody M, Eriksson J, Meadows J, Sherwood E, Webster M, et al.
Nature
. 2010 Mar;
464(7288):587-91.
PMID: 20220755
Domestic animals are excellent models for genetic studies of phenotypic evolution. They have evolved genetic adaptations to a new environment, the farm, and have been subjected to strong human-driven selection...
19.
Haas B, Kamoun S, Zody M, Jiang R, Handsaker R, Cano L, et al.
Nature
. 2009 Sep;
461(7262):393-8.
PMID: 19741609
Phytophthora infestans is the most destructive pathogen of potato and a model organism for the oomycetes, a distinct lineage of fungus-like eukaryotes that are related to organisms such as brown...
20.
Mikkelsen T, Wakefield M, Aken B, Amemiya C, Chang J, Duke S, et al.
Nature
. 2007 May;
447(7141):167-77.
PMID: 17495919
We report a high-quality draft of the genome sequence of the grey, short-tailed opossum (Monodelphis domestica). As the first metatherian ('marsupial') species to be sequenced, the opossum provides a unique...