Tatyana Chtanova
Overview
Explore the profile of Tatyana Chtanova including associated specialties, affiliations and a list of published articles.
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37
Citations
1657
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Recent Articles
1.
Chambers C, Watakul S, Schofield P, Howell A, Zhu J, Tran A, et al.
Sci Adv
. 2025 Mar;
11(11):eadq4416.
PMID: 40073121
Pancreatic cancer (PC) is a highly metastatic malignancy. More than 80% of patients with PC present with advanced-stage disease, preventing potentially curative surgery. The neuropeptide Y (NPY) system, best known...
2.
Copper chelation redirects neutrophil function to enhance anti-GD2 antibody therapy in neuroblastoma
Rouaen J, Salerno A, Shai-Hee T, Murray J, Castrogiovanni G, McHenry C, et al.
Nat Commun
. 2024 Dec;
15(1):10462.
PMID: 39668192
Anti-disialoganglioside (GD2) antibody therapy has provided clinical benefit to patients with neuroblastoma however efficacy is likely impaired by the immunosuppressive tumor microenvironment. We have previously defined a link between intratumoral...
3.
Yam A, Jakovija A, Gatt C, Chtanova T
Front Immunol
. 2024 Oct;
15:1458035.
PMID: 39439807
Neutrophils rapidly respond to inflammation resulting from infection, injury, and cancer. Intravital microscopy (IVM) has significantly advanced our understanding of neutrophil behavior, enabling real-time visualization of their migration, interactions with...
4.
Kusumoto Y, Ueda M, Hashimoto M, Takeuchi H, Okada N, Yamamoto J, et al.
JCI Insight
. 2024 Oct;
9(21).
PMID: 39352752
The oral mucosa is the first line of defense against pathogenic bacteria and plays a vital role in maintaining tolerance to food antigens and commensal bacteria. We used CD11c reporter...
5.
Jakovija A, Chtanova T
Front Immunol
. 2023 Jul;
14:1060258.
PMID: 37398649
The skin is the body's largest organ. It serves as a barrier to pathogen entry and the first site of immune defense. In the event of a skin injury, a...
6.
Rogers N, Zammit N, Nguyen-Ngo D, Souilmi Y, Minhas N, Meijles D, et al.
Kidney Int
. 2023 Apr;
103(6):1105-1119.
PMID: 37097268
Nuclear factor κB (NF-κB) activation is a deleterious molecular mechanism that drives acute kidney injury (AKI) and manifests in transplanted kidneys as delayed graft function. The TNFAIP3 gene encodes A20,...
7.
Rojas-Canales D, Walters S, Penko D, Cultrone D, Bailey J, Chtanova T, et al.
Diabetes
. 2023 Mar;
72(6):758-768.
PMID: 36929171
Article Highlights: Human and porcine pancreatic islets were transplanted into a fully vascularized biodegradable temporizing matrix (Novosorb) that creates a unique intracutaneous site outside of the liver in a large-animal...
8.
Yam A, Bailey J, Lin F, Jakovija A, Youlten S, Counoupas C, et al.
Cancer Res
. 2023 Feb;
83(8):1315-1328.
PMID: 36787115
Significance: Intratumoral injection of microbial bioparticles stimulates neutrophil antitumor functions, suggesting pathways for optimizing efficacy of microbial therapies and paving the way for their broader utilization in the clinic.
9.
Bartonicek N, Rouet R, Warren J, Loetsch C, Rodriguez G, Walters S, et al.
Nature
. 2022 Aug;
608(7924):757-765.
PMID: 35948641
The notion that mobile units of nucleic acid known as transposable elements can operate as genomic controlling elements was put forward over six decades ago. However, it was not until...
10.
Moriya T, Hashimoto M, Matsushita H, Masuyama S, Yoshida R, Okada R, et al.
Cancer Immunol Immunother
. 2022 May;
71(12):3099-3106.
PMID: 35624180
Near-infrared photoimmunotherapy (NIR-PIT) selectively kills tumor cells to which the photo-absorber dye IR700DX-conjugated antibodies are bound and induces a systemic anti-tumor immune response. NIR-PIT induces immunogenic cell death (ICD), releases...