Tatsushi Muta
Overview
Explore the profile of Tatsushi Muta including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
1246
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0
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Recent Articles
1.
Maruyama T, Sayama A, Ishii K, Muta T
Biochem Biophys Res Commun
. 2015 Dec;
469(3):711-5.
PMID: 26711529
Posttranscriptional regulatory elements in the 3'-untranslated region (UTR) of mRNAs play an important role in mRNA stabilization. Induction of IκB-ζ, a critical transcriptional regulator in the innate immune response, is...
2.
Maruyama T, Kobayashi S, Ogasawara K, Yoshimura A, Chen W, Muta T
J Leukoc Biol
. 2015 May;
98(3):385-93.
PMID: 26019294
The transcriptional regulator IκB-ζ is important for the control of apoptosis in keratinocytes. Thus, IκB-ζ-deficient mice develop autoimmune diseases, such as Sjögren's syndrome. However, T cells also play a pivotal...
3.
Kimura T, Kobayashi S, Hanihara-Tatsuzawa F, Sayama A, Maruyama T, Muta T
Int Immunol
. 2014 Aug;
26(12):697-704.
PMID: 25096411
The immune system maintains homeostasis by recognizing and responding to cell death caused by various stresses. The immune response is considered to be elicited by 'danger signals' released from necrotic...
4.
Hanihara F, Takahashi Y, Okuma A, Ohba T, Muta T
Int Immunol
. 2013 Jun;
25(9):531-44.
PMID: 23728777
IκB-ζ is a nuclear IκB protein robustly induced in macrophages and fibroblasts upon TLR or IL-1R stimulation. IκB-ζ associates with NF-κB in the cell nucleus and is essential for the...
5.
Kanari Y, Sato Y, Aoyama S, Muta T
PLoS One
. 2013 Mar;
8(3):e59026.
PMID: 23520550
Whereas accumulating evidence indicates that a number of inflammatory genes are induced by activation of nuclear factor-κB and other transcription factors, less is known about genes that are suppressed by...
6.
Ryzhakov G, Teixeira A, Saliba D, Blazek K, Muta T, Ragoussis J, et al.
J Biol Chem
. 2013 Mar;
288(16):11546-54.
PMID: 23508954
NF-κB is a key regulator of immune gene expression in metazoans. It is currently unclear what changes occurred in NF-κB during animal evolution and what features remained conserved. To address...
7.
Okuma A, Hoshino K, Ohba T, Fukushi S, Aiba S, Akira S, et al.
Immunity
. 2013 Mar;
38(3):450-60.
PMID: 23453632
Sjögren's syndrome (SS) is an autoimmune disease characterized by exocrinopathy that leads to dry eye and mouth. Although lymphocyte infiltration into exocrine glands and the generation of autoantibodies have been...
8.
Kanno A, Yamamoto C, Onji M, Fukui R, Saitoh S, Motoi Y, et al.
Int Immunol
. 2013 Mar;
25(7):413-22.
PMID: 23446849
Toll-like receptor 7 (TLR7) an innate immune sensor for microbial RNA, erroneously responds to self-derived RNA. To avoid autoimmune responses, TLR7 is suggested to be silenced until the N-terminal half...
9.
Jung M, Weigert A, Tausendschon M, Mora J, Oren B, Sola A, et al.
Mol Cell Biol
. 2012 Aug;
32(19):3938-48.
PMID: 22851691
Tumor cell-derived factors, such as interleukin 10 (IL-10), polarize macrophages toward a regulatory M2 phenotype, characterized by the expression of anti-inflammatory cytokines and protumorigenic mediators. Here we explored molecular mechanisms...
10.
Zhu J, Weinberg R, Wu X, Gowda N, Muta T, Gowda D
IUBMB Life
. 2011 Dec;
64(2):187-93.
PMID: 22131231
Plasmodium falciparum glycosylphosphatidylinositols (GPIs) have been proposed as malaria pathogenic factors based on their ability to induce proinflammatory responses in macrophages and malaria-like symptoms in mice. Parasite GPIs induce the...