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Tasmia Ahmed

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Articles 11
Citations 45
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Recent Articles
1.
Ortiz H, Cruz Flores P, Podgorski J, Ramonett A, Ahmed T, Hempel N, et al.
Neoplasia . 2024 May; 53:101003. PMID: 38759377
Dynamic changes in the endoplasmic reticulum (ER) morphology are central to maintaining cellular homeostasis. Microtubules (MT) facilitate the continuous remodeling of the ER network into sheets and tubules by coordinating...
2.
Cruz Flores P, Ahmed T, Podgorski J, Ortiz H, Langlais P, Mythreye K, et al.
Biochem Biophys Res Commun . 2024 Apr; 711:149916. PMID: 38613866
βIV-spectrin is a membrane-associated cytoskeletal protein that maintains the structural stability of cell membranes and integral proteins such as ion channels and transporters. Its biological functions are best characterized in...
3.
Havas A, Tula-Sanchez A, Steenhoek H, Bhakta A, Wingfield T, Huntley M, et al.
Transl Oncol . 2023 Oct; 39:101779. PMID: 37865047
Approved histone deacetylase (HDAC) inhibitors have low efficacy against the most commonly-diagnosed non-Hodgkin lymphoma, diffuse large B cell lymphoma (DLBCL), but the mechanisms underlying clinical resistance are poorly understood. Using...
4.
Kwak E, Ahmed T, Cruz Flores P, Ortiz H, Langlais P, Mythreye K, et al.
Cancer Med . 2023 Sep; 12(18):18981-18987. PMID: 37680049
Background: Tumor-associated angiogenesis mediates the growth and metastasis of most solid cancers. Targeted therapies of the VEGF pathways can effectively block these processes but often fail to provide lasting benefits...
5.
Ortiz H, Cruz Flores P, Ramonett A, Ahmed T, Ellis N, Langlais P, et al.
bioRxiv . 2023 May; PMID: 37131821
Dynamic changes in the endoplasmic reticulum (ER) morphology are central to maintaining cellular homeostasis. Microtubules (MT) facilitate the continuous remodeling of the ER network into sheets and tubules by coordinating...
6.
Ahmed T, Ramonett A, Kwak E, Kumar S, Cruz Flores P, Ortiz H, et al.
Mol Biol Cell . 2023 May; 34(7):ar72. PMID: 37126382
β-Spectrin is a membrane cytoskeletal protein with specialized roles in the nervous system and heart. Recent evidence also indicates a fundamental role for β-spectrin in angiogenesis as its endothelial-specific gene...
7.
Ahmed T, Cruz Flores P, Pan C, Ortiz H, Lee Y, Langlais P, et al.
J Biol Chem . 2022 Jul; 298(9):102297. PMID: 35872017
Insulin signaling in blood vessels primarily functions to stimulate angiogenesis and maintain vascular homeostasis through the canonical PI3K and MAPK signaling pathways. However, angiogenesis is a complex process coordinated by...
8.
Kwak E, Pan C, Ramonett A, Kumar S, Cruz-Flores P, Ahmed T, et al.
Nat Commun . 2022 Mar; 13(1):1326. PMID: 35288568
Defective angiogenesis underlies over 50 malignant, ischemic and inflammatory disorders yet long-term therapeutic applications inevitably fail, thus highlighting the need for greater understanding of the vast crosstalk and compensatory mechanisms....
9.
Ramonett A, Kwak E, Ahmed T, Cruz Flores P, Ortiz H, Lee Y, et al.
Mol Biol Cell . 2021 Oct; 33(1):ar4. PMID: 34705526
Dynamin-related protein 1 (Drp1) is a key regulator of mitochondrial fission, a large cytoplasmic GTPase recruited to the mitochondrial surface via transmembrane adaptors to initiate scission. While Brownian motion likely...
10.
Ahmed T, Rahman S, Asaduzzaman M, Islam A, Chowdhury A
Pharmacol Res Perspect . 2021 Jun; 9(3):e00800. PMID: 34086411
Antiprotozoal drug nitazoxanide (NTZ) has shown diverse pharmacological properties and has appeared in several clinical trials. Herein we present the synthesis, characterization, in vitro biological investigation, and in silico study...