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Karthikeyan Mythreye

Explore the profile of Karthikeyan Mythreye including associated specialties, affiliations and a list of published articles. Areas
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Articles 62
Citations 1292
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Recent Articles
1.
Cheng Y, Worley B, Javed Z, Elhaw A, Tang P, Al-Saad S, et al.
bioRxiv . 2024 Nov; PMID: 39605523
Myelin protein zero-like 3 (MPZL3) is an Immunoglobulin-containing transmembrane protein with predicted cell adhesion molecule function. Loss of 11q23, where the gene resides, is frequently observed in cancer, and copy...
2.
Evans E, Page E, Choi A, Shonibare Z, Kahn A, Arend R, et al.
Cancer Med . 2024 Sep; 13(17):e7368. PMID: 39248018
Objective: The TGF-β superfamily member activin, a dimer of the gene products of INHBA and/or INHBB, has been implicated in immune cell maturation and recruitment, but its immune impact within...
3.
Javed Z, Shin D, Pan W, White S, Elhaw A, Kim Y, et al.
EMBO Rep . 2024 Aug; 25(10):4281-4310. PMID: 39191946
Aberrant mitochondrial fission/fusion dynamics are frequently associated with pathologies, including cancer. We show that alternative splice variants of the fission protein Drp1 (DNM1L) contribute to the complexity of mitochondrial fission/fusion...
4.
Dinkins K, Barton W, Wheeler L, Smith H, Mythreye K, Arend R
Gynecol Oncol Rep . 2024 Aug; 54:101450. PMID: 39092168
Ovarian cancer continues to have a high mortality rate despite therapeutic advances. Traditionally, treatment has focused on surgery followed by systemic platinum- based chemotherapy. Unfortunately, most patients develop resistance to...
5.
Ortiz H, Cruz Flores P, Podgorski J, Ramonett A, Ahmed T, Hempel N, et al.
Neoplasia . 2024 May; 53:101003. PMID: 38759377
Dynamic changes in the endoplasmic reticulum (ER) morphology are central to maintaining cellular homeostasis. Microtubules (MT) facilitate the continuous remodeling of the ER network into sheets and tubules by coordinating...
6.
Cruz Flores P, Ahmed T, Podgorski J, Ortiz H, Langlais P, Mythreye K, et al.
Biochem Biophys Res Commun . 2024 Apr; 711:149916. PMID: 38613866
βIV-spectrin is a membrane-associated cytoskeletal protein that maintains the structural stability of cell membranes and integral proteins such as ion channels and transporters. Its biological functions are best characterized in...
7.
Choi A, Jenkins-Lane L, Barton W, Kumari A, Lancaster C, Raulerson C, et al.
Cell Commun Signal . 2024 Feb; 22(1):128. PMID: 38360757
In pathologies including cancer, aberrant Transforming Growth Factor-β (TGF-β) signaling exerts profound tumor intrinsic and extrinsic consequences. Intense clinical endeavors are underway to target this pathway. Central to the success...
8.
Chang C, Cheng Y, Kamlapurkar S, White S, Tang P, Elhaw A, et al.
bioRxiv . 2024 Feb; PMID: 38352432
Objective: We previously reported that high expression of the extracellular glutathione peroxidase GPX3 is associated with poor patient outcome in ovarian serous adenocarcinomas, and that GPX3 protects ovarian cancer cells...
9.
Chang C, Cheng Y, Kamlapurkar S, White S, Tang P, Elhaw A, et al.
Gynecol Oncol . 2024 Feb; 185:8-16. PMID: 38342006
Objective: We previously reported that high expression of the extracellular glutathione peroxidase GPX3 is associated with poor patient outcome in ovarian serous adenocarcinomas, and that GPX3 protects ovarian cancer cells...
10.
Monavarian M, Page E, Rajkarnikar R, Kumari A, Macias L, Massicano F, et al.
bioRxiv . 2023 Dec; PMID: 38106208
Anoikis resistance or evasion of cell death triggered by cell detachment into suspension is a hallmark of cancer that is concurrent with cell survival and metastasis. The effects of frequent...