Taru A Muranen
Overview
Explore the profile of Taru A Muranen including associated specialties, affiliations and a list of published articles.
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65
Citations
3966
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Recent Articles
1.
Morra A, Schreurs M, Andrulis I, Anton-Culver H, Augustinsson A, Beckmann M, et al.
Cancer Med
. 2023 Jul;
12(15):16142-16162.
PMID: 37401034
Background: Breast cancer (BC) patients with a germline CHEK2 c.1100delC variant have an increased risk of contralateral BC (CBC) and worse BC-specific survival (BCSS) compared to non-carriers. Aim: To assessed...
2.
Lahtinen A, Lavikka K, Virtanen A, Li Y, Jamalzadeh S, Skorda A, et al.
Cancer Cell
. 2023 May;
41(6):1103-1117.e12.
PMID: 37207655
Ovarian high-grade serous carcinoma (HGSC) is typically diagnosed at an advanced stage, with multiple genetically heterogeneous clones existing in the tumors long before therapeutic intervention. Herein we integrate clonal composition...
3.
Muranen T, Morra A, Khan S, Barnes D, Bolla M, Dennis J, et al.
NPJ Breast Cancer
. 2023 May;
9(1):37.
PMID: 37173335
We assessed the PREDICT v 2.2 for prognosis of breast cancer patients with pathogenic germline BRCA1 and BRCA2 variants, using follow-up data from 5453 BRCA1/2 carriers from the Consortium of...
4.
Morra A, Mavaddat N, Muranen T, Ahearn T, Allen J, Andrulis I, et al.
Am J Hum Genet
. 2023 Feb;
110(3):475-486.
PMID: 36827971
Evidence linking coding germline variants in breast cancer (BC)-susceptibility genes other than BRCA1, BRCA2, and CHEK2 with contralateral breast cancer (CBC) risk and breast cancer-specific survival (BCSS) is scarce. The...
5.
Morra A, Schreurs M, Andrulis I, Anton-Culver H, Augustinsson A, Beckmann M, et al.
Res Sq
. 2023 Feb;
PMID: 36824750
Breast cancer (BC) patients with a germline c.1100delC variant have an increased risk of contralateral BC (CBC) and worse BC-specific survival (BCSS) compared to non-carriers. We aimed to assess the...
6.
Mavaddat N, Dorling L, Carvalho S, Allen J, Gonzalez-Neira A, Keeman R, et al.
JAMA Oncol
. 2022 Jan;
8(3):e216744.
PMID: 35084436
Importance: Rare germline genetic variants in several genes are associated with increased breast cancer (BC) risk, but their precise contributions to different disease subtypes are unclear. This information is relevant...
7.
Dennis J, Tyrer J, Walker L, Michailidou K, Dorling L, Bolla M, et al.
Commun Biol
. 2022 Jan;
5(1):65.
PMID: 35042965
Germline copy number variants (CNVs) are pervasive in the human genome but potential disease associations with rare CNVs have not been comprehensively assessed in large datasets. We analysed rare CNVs...
8.
Escala-Garcia M, Canisius S, Keeman R, Beesley J, Anton-Culver H, Arndt V, et al.
Sci Rep
. 2021 Oct;
11(1):19787.
PMID: 34611289
Breast cancer metastasis accounts for most of the deaths from breast cancer. Identification of germline variants associated with survival in aggressive types of breast cancer may inform understanding of breast...
9.
Morra A, Escala-Garcia M, Beesley J, Keeman R, Canisius S, Ahearn T, et al.
Breast Cancer Res
. 2021 Aug;
23(1):86.
PMID: 34407845
Background: Given the high heterogeneity among breast tumors, associations between common germline genetic variants and survival that may exist within specific subgroups could go undetected in an unstratified set of...
10.
Park H, Neumeyer S, Michailidou K, Bolla M, Wang Q, Dennis J, et al.
Br J Cancer
. 2021 Aug;
125(8):1135-1145.
PMID: 34341517
Background: Despite a modest association between tobacco smoking and breast cancer risk reported by recent epidemiological studies, it is still equivocal whether smoking is causally related to breast cancer risk....